Protein Alignment CG30287 and KLK5

DIOPT Version :10

• Sequence 1: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 79/258 - (30%)
• Similarity: 122/258 - (47%)
• Gaps: 41/258 - (15%)

  Fly    33 ARSEPGLYRVINGKPADLFSNPWMVIIIER-GMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLG 96
            |||:....|:|||...|:.:.||...::.| ..:.||..|:.|:::||||||:   |....||||
Human    58 ARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR---KKVFRVRLG 119

  Fly    97 DYDVNQAVDC-----SSYGCIPRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSIC 156
            .|.::...:.     .....||.|...:      |.|     .||:.|::|...::...::|.|.
Human   120 HYSLSPVYESGQQMFQGVKSIPHPGYSH------PGH-----SNDLMLIKLNRRIRPTKDVRPIN 173

  Fly   157 LLMGDYTWSSNILKNLVKFNTTGWGRTES-RINSP-VLQQASLTHHHLSYCAQVFGKQLDKSHIC 219
            :       ||:......|...:|||.|:| :::.| |||..:::......|...:.:|:|.:..|
Human   174 V-------SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFC 231

  Fly   220 VASSTG-STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFGPT---VYTNVIHFANWIE 278
            .....| .:||||||||:...   ||     |.|:||:|...|..|.   ||||:..|..||:
Human   232 AGDKAGRDSCQGDSGGPVVCN---GS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	75/249 (30%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/9 (44%)
		Tryp_SPc	66..285	CDD:214473	74/247 (30%)