Protein Alignment CG30287 and F10

DIOPT Version :10

• Sequence 1: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 83/290 - (28%)
• Similarity: 121/290 - (41%)
• Gaps: 71/290 - (24%)

  Fly    25 LLD-PQCVTARSEPGLYRVINGKPADLFSNPWMVIII-ERGMMKCGGSLITPRYVLTAAHCKSET 87
            ||| .|....|.:..|.|::.|:.......||..::| |.....|||::::..|:||||||..:.
Human   217 LLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQA 281

  Fly    88 KSQLTVRLGDYDVNQ-----AVDCSSYGCIPRPREINVTRTYVPSHYTNFRKN----DIALLRLE 143
            | :..||:||.:..|     ||           .|:.|    |..| ..|.|.    |||:|||:
Human   282 K-RFKVRVGDRNTEQEEGGEAV-----------HEVEV----VIKH-NRFTKETYDFDIAVLRLK 329

  Fly   144 TTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESR----------------INSPVL 192
            |.:.:..|:...||...|  |:.:.|........:|:|||..:                .||..|
Human   330 TPITFRMNVAPACLPERD--WAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKL 392

  Fly   193 QQASLTHHHLSYCAQVFGKQLDKSHICVASSTGSTCQGDSGGPLTARVRIGSERRVILFGVVSYG 257
            ..:.:...:: :||....||.|            .||||||||...|.:    ....:.|:||:|
Human   393 SSSFIITQNM-FCAGYDTKQED------------ACQGDSGGPHVTRFK----DTYFVTGIVSWG 440

  Fly   258 AVHC-----FGPTVYTNVIHFANWIELHTK 282
            . .|     :|  :||.|..|..||:...|
Human   441 E-GCARKGKYG--IYTKVTAFLKWIDRSMK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	75/268 (28%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	75/267 (28%)
		O-glycosylated at one site	476..485