DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and Mst1

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	272	Identity:	76/272 - (27%)
Similarity:	112/272 - (41%)	Gaps:	42/272 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PHLLDP-------QCVTARSEPGLYRVINGKPADLFSNPWMVIIIER-GMMKCGGSLITPRYVLT 79
            |.:|||       :|.....:....||:.|.|.   ::||.|.:..| |...|||||:..::|||
Mouse   463 PSILDPPDQVVFEKCGKRVDKSNKLRVVGGHPG---NSPWTVSLRNRQGQHFCGGSLVKEQWVLT 524

  Fly    80 AAHCKSETKSQLT---VRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVPSHYTNFRKNDIALLR 141
            |..|.......||   |.||..:.|           |:|.|.|:.|..|.........:.:.||:
Mouse   525 ARQCIWSCHEPLTGYEVWLGTINQN-----------PQPGEANLQRVPVAKAVCGPAGSQLVLLK 578

  Fly   142 LETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHHLSYCA 206
            ||..|....::..|||....|     ::....|....|||.:....|:.||..||:.......|.
Mouse   579 LERPVILNHHVALICLPPEQY-----VVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECN 638

  Fly   207 QVFGKQLDKSHIC---VASSTGSTCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCF---GPT 265
            ..:...:.:|.||   :....|: |:||.||||...    :....:|.|::....| |.   .|.
Mouse   639 TKYRGHIQESEICTQGLVVPVGA-CEGDYGGPLACY----THDCWVLQGLIIPNRV-CARPRWPA 697

  Fly   266 VYTNVIHFANWI 277
            ::|.|..|.:||
Mouse   698 IFTRVSVFVDWI 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	69/245 (28%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	70/246 (28%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	69/245 (28%)
		Tryp_SPc	489..712	CDD:238113	70/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930