DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30287 and Hgf

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	269	Identity:	74/269 - (27%)
Similarity:	113/269 - (42%)	Gaps:	76/269 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RVINGKPADLFSNPWMVIIIERGMMKCGGSLITPRYVLTAAHC---KSETKSQLTVRLGDYDVNQ 102
            ||:||.|... :..|||.:..|....||||||...:||||..|   :::........||.:||::
Mouse   495 RVVNGIPTQT-TVGWMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHE 558

  Fly   103 AVDCSSYGCIPRPREINVTR-TYVPSHYTNFRKNDIALLRLE---------TTV---QYGDNI-- 152
            .      |...|.:.:|::: .|.|      ..:|:.||:|.         :|:   .||..|
Mouse   559 R------GEEKRKQILNISQLVYGP------EGSDLVLLKLARPAILDNFVSTIDLPSYGCTIPE 611

  Fly   153 RSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSP-VLQQASL--------THHHLSYCAQV 208
            ::.|.:.                   |||.| ..||:. :|:.|.|        :.||.
Mouse   612 KTTCSIY-------------------GWGYT-GLINADGLLRVAHLYIMGNEKCSQHHQ------ 650

  Fly   209 FGK-QLDKSHICV-ASSTGS-TCQGDSGGPLTARVRIGSERRVILFGVV--SYGAVHCFGPTVYT 268
             || .|::|.:|. |...|| .|:||.||||.....   :.|::| ||:  ..|......|.::.
Mouse   651 -GKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQH---KMRMVL-GVIVPGRGCAIPNRPGIFV 710

  Fly   269 NVIHFANWI 277
            .|.::|.||
Mouse   711 RVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	72/267 (27%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	73/268 (27%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	72/267 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833149
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930