DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and AgaP_AGAP001366

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_321777.4	Gene:	AgaP_AGAP001366 / 1281814	VectorBaseID:	AGAP001366	Length:	563	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	76/283 - (26%)
Similarity:	118/283 - (41%)	Gaps:	38/283 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GQPHLLDPQ----C--VTARSEPGLYRVINGKPADLFSNPWMVIIIERGMMK----CGGSLITPR 75
            ||.|.::..    |  |..::.|   .|.:|..::....||...:....:.:    ||.:||:.|
Mosquito   291 GQTHYINKYEGDICGTVVPKANP---LVTHGTVSERGQFPWHGALYRSTVTELKYLCGATLISRR 352

  Fly    76 YVLTAAHCKSETKSQLTVRLGDYDVN-QAVDCSSYGCIPRPRE-INVTRTYVPSHYTNFR-KNDI 137
            ..:|||||.:..||...|..|...:. ..:|.|.:.   .|.| ..:...::|:.|.:.| .|||
Mosquito   353 ASITAAHCVTLEKSSKPVDAGSLLLYFGKIDLSKWN---GPEEDAQIRSIHIPAQYQHERFFNDI 414

  Fly   138 ALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHHL 202
            |:|.|:..::|.:.:|.:||...|..:.:  |.|.:.| ..|||..|..:.|..|..|.:.....
Mosquito   415 AVLVLKEDIKYSNFVRPVCLWNFDDDYKT--LINKIGF-VPGWGYNEHGLVSSRLSFAQMPVVAH 476

  Fly   203 SYC----AQVFGKQLDKSHICVASSTG-STCQGDSGGPLTARVRIGSERRVILFGVVSYGAV--- 259
            ..|    ...|.|....:..|.....| |.|.|||||.:..:    ......|.|:||..|.
Mosquito   477 ETCIWSNRDFFSKVTSDTSFCAGFKNGTSVCNGDSGGGMVFK----HNNLWYLRGIVSVSAALQD 537

  Fly   260 --HCFGP--TVYTNVIHFANWIE 278
              ||...  .|:|:...|.:||:
Mosquito   538 RFHCDSKHYVVFTDAAKFTSWIK 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	68/254 (27%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	70/256 (27%)
AgaP_AGAP001366	XP_321777.4	GD_N	15..124	CDD:292649
		Tryp_SPc	315..560	CDD:238113	69/254 (27%)
		Tryp_SPc	315..559	CDD:214473	68/253 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910