DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and AgaP_AGAP012022

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_320504.4	Gene:	AgaP_AGAP012022 / 1280645	VectorBaseID:	AGAP012022	Length:	737	Species:	Anopheles gambiae

Alignment Length:	224	Identity:	67/224 - (29%)
Similarity:	102/224 - (45%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 CGGSLITPRYVLTAAHCKSETKS--QLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVPSHY 129
            ||||||...::||||||.::..:  ....|:||.::....|..   ...:.:.:.:.|.  |.|.
Mosquito    50 CGGSLIWENFILTAAHCAADDNNVPPDVARMGDINIYSDEDDE---FAQQLKIVEIIRH--PKHK 109

  Fly   130 TNFRKNDIALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRT---ESRINSPV 191
            .|....||||::||..|...:.:...||.:.|......:|       ..|||||   |....:.:
Mosquito   110 YNSNYYDIALMKLERNVTLHNTVAPTCLWLDDEIRFPELL-------AAGWGRTGFGEDTTKTLL 167

  Fly   192 -LQQASLTHHHLSYCAQVFGKQLDKS----HICVASSTGSTCQGDSGGPLTARVRIGSERRVI-- 249
             :|.|.:|:...|...|...::|:..    ..|.......||.|||||||  .|::..:.:::
Mosquito   168 KVQLAPITNDKCSTHYQRGVRKLENGLMDHQFCAGDEKMDTCPGDSGGPL--HVKLFKKWKLVPF 230

  Fly   250 LFGVVSYG-AVHCFGPTVYTNVIHFANWI 277
            |.||.|:| |.....|.||..|..|::||
Mosquito   231 LVGVTSFGKACGISAPGVYVKVSKFSDWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	65/222 (29%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	67/224 (30%)
AgaP_AGAP012022	XP_320504.4	Tryp_SPc	23..262	CDD:238113	67/224 (30%)
		Tryp_SPc	23..259	CDD:214473	65/222 (29%)
		Tryp_SPc	335..533	CDD:304450
		Tryp_SPc	648..>729	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910