DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and AgaP_AGAP008911

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_319658.4	Gene:	AgaP_AGAP008911 / 1279878	VectorBaseID:	AGAP008911	Length:	579	Species:	Anopheles gambiae

Alignment Length:	311	Identity:	83/311 - (26%)
Similarity:	132/311 - (42%)	Gaps:	67/311 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QLLLLIALVFL--KVQGQPHLLDPQCVTARSEPGLYRVINGKPADLFSNPWMVIIIERGMMK--- 66
            |.|||:..::|  :::||.   :.|.:..|.:.....:.|...|.....||...|..|...|
Mosquito     7 QYLLLMGCLYLVTQIRGQD---EDQLLCGRRKVQTNSMNNNGDAIAGHWPWYAAIYHRKGEKQEY 68

  Fly    67 -CGGSLITPRYVLTAAHCKSE-----TKSQLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYV 125
             ||||::....:|||::|...     :.:.:||.:|.....||   |:|..:...|||.|
Mosquito    69 ACGGSILDETTILTASNCVYTPSGVISAALVTVHVGQIHPKQA---SAYAQMYDVREIVV----- 125

  Fly   126 PSHYTNFRK----NDIALLRLET----TVQYGDNIRSICLLMGDYTWS-SNILKNLVKFNTT--G 179
               :..|.:    |||||::|..    |.:|   ::.:||      |: .:.|:.:|..|.|  |
Mosquito   126 ---HPGFSEASTINDIALIKLTASITLTTEY---VQPVCL------WTMDSALELIVGRNGTVVG 178

  Fly   180 WGRTESR--INSPVLQQASLTHHHLSYC----AQVFGKQLDKSHIC---VASSTGSTCQGDSGGP 235
            :|..|.|  ::...||||::.......|    ..:||..|.....|   :.:..|: |.||||..
Mosquito   179 FGPNERRDVVSGEQLQQATIGVVDPQTCIASDPAIFGTHLPVETFCGKGLQNGAGA-CNGDSGDG 242

  Fly   236 LTARVRIGSERRVILFGVV--------SYGAVHCFGPTVYTNVIHFANWIE 278
            |...|    ..:..:.|:|        |.|.......||||:|..:.:||:
Mosquito   243 LFFEV----SGQWFVRGLVARLQPVRESDGLCDPLQYTVYTDVAKYVDWIK 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	72/272 (26%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	74/274 (27%)
AgaP_AGAP008911	XP_319658.4	Tryp_SPc	359..573	CDD:304450
		Tryp_SPc	46..290	CDD:238113	73/269 (27%)
		Tryp_SPc	46..288	CDD:214473	71/266 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910