DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	238	Identity:	70/238 - (29%)
Similarity:	110/238 - (46%)	Gaps:	33/238 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PWMVIIIER---GMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDYDVNQAVDCSS-YG---C 111
            ||||.:..:   ..:.|.|.|:...|||| |.| .:.:.::|..|||||.::..||.. ||   |
Mosquito   345 PWMVALQAKTTTEYVPCNGVLLNRNYVLT-AEC-YDLQYEITATLGDYDTSRTKDCGKVYGNMQC 407

  Fly   112 IPRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYG--DNIRSICLLMGDYTWSSNI-LKNLV 173
            :...:.::|::.        .||:|:.|:||......|  .||.:|||   ..|....| |.|
Mosquito   408 LSAVQTVSVSQF--------IRKDDLVLVRLSDPADIGRRQNIEAICL---PVTPEQRIRLYN-- 459

  Fly   174 KFNTTGWGRTESRINSPVLQQASLTHHHLSYCAQVFGKQLDKSHICVAS----STGSTCQGDSGG 234
            ::..|||  .||..::.:||:|.|....|:.|...|..::|...|||.:    :....|...:.|
Mosquito   460 RYIMTGW--KESGSDATILQRALLEAIDLNKCRAKFKGRIDSKTICVWNLEDPNRSVACNDYTPG 522

  Fly   235 PLTARVRIGSERRVILFGVVSYGAVHCFGPTVYTNVIHFANWI 277
            .....:...| :|.:|:||:.| ..:|..|..|..:..:..||
Mosquito   523 SALQAIDQKS-KRYLLYGVLRY-ISYCSVPEQYIAISEYLLWI 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	68/236 (29%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	70/238 (29%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113
		Tryp_SPc	50..297	CDD:214473
		Tryp_SPc	342..563	CDD:214473	68/236 (29%)
		Tryp_SPc	342..563	CDD:304450	68/236 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910