DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and F11

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	277	Identity:	91/277 - (32%)
Similarity:	122/277 - (44%)	Gaps:	62/277 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LDPQCVTARSEPGLYRVINGKPADLFSNPWMVII-IERGMMKCGGSLITPRYVLTAAHCKS--ET 87
            :|..| |.:..|   ||:.|..:.....||.|.: |.:|.: ||||:|..:::||||||.|  ||
Mouse   378 MDNVC-TTKINP---RVVGGAASVHGEWPWQVTLHISQGHL-CGGSIIGNQWILTAAHCFSGIET 437

  Fly    88 KSQLTVRLGDYDVNQAVDCSSYGCIPRPREIN-------VTRTYVPSHYTNFRKN-DIALLRLET 144
            ..:|.|               ||.|....|||       |....:...||..... |||||:||:
Mouse   438 PKKLRV---------------YGGIVNQSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLES 487

  Fly   145 TVQYGDNIRSICL-LMGDYTWSSNILKNLVKFN--TTGWGRTESR--INSPVLQQASLTHHHLSY 204
            .:.|.|..|.||| ..||        :|.|...  .||||.|..|  :.| .||:|.:.......
Mouse   488 AMNYTDFQRPICLPSKGD--------RNAVHTECWVTGWGYTALRGEVQS-TLQKAKVPLVSNEE 543

  Fly   205 CAQVFGK-QLDKSHICVASSTG--STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFG--- 263
            |...:.: ::....||.....|  .||:|||||||:.:.. |...   |.|:.|:|.    |
Mouse   544 CQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYN-GVWH---LVGITSWGE----GCGQ 600

  Fly   264 ---PTVYTNVIHFANWI 277
               |.|||||..:.:||
Mouse   601 KERPGVYTNVAKYVDWI 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	85/260 (33%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	86/261 (33%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519
		Tryp_SPc	389..617	CDD:214473	85/260 (33%)
		Tryp_SPc	390..617	CDD:238113	84/259 (32%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910