Protein Alignment CG30284 and GRAMD2B

DIOPT Version :10

• Sequence 1: NP_726097.1
• Gene: CG30284 / 246527
• FlyBaseID: FBgn0050284
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_011541895.1
• Gene: GRAMD2B / 65983
• HGNCID: 24911
• Length: 448
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 101/463 - (21%)
• Similarity: 157/463 - (33%)
• Gaps: 153/463 - (33%)

  Fly     2 KSIQARL-------NHRFRKTLAMDKPSSSNSNRMSRSTSNCRSPAIIRSPLNSEEFQDSATAAA 59
            ::.||:|       :.|..|.:..|...|...|.:......||||. .:||..|.| .||    .
Human    16 QTFQAQLMPWKSMFHGREVKPVGPDLELSEAENGVEEKKKACRSPT-AQSPTPSVE-ADS----P 74

  Fly    60 TQQRL--FWSGQRASTAGRDDKTKPDSTAAGKKKPPTTTRQSNFTQTERRRT------------H 110
            .|:::  .||           |:..|..:....|....|...|..:|||:::            |
Human    75 DQKKIISLWS-----------KSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFH 128

  Fly   111 RK-LSPRSTRCNSVAVTALVSRENIPQTSGKRGKKTPSH-----------RSTLISTP--SKTLQ 161
            :. ||..:......:.|..:.:|.:.|     ||...|.           :.|.||.|  |.||.
Human   129 KLFLSVPTEEPLKQSFTCALQKEILYQ-----GKLFVSENWICFHSKVFGKDTKISIPAFSVTLI 188

  Fly   162 LKTAAGYRRPEDLTARCSASHEGRKLLQERLMVRVDALFNMLFSASPFLQ--------------- 211
            .||......|..|..   |:...|.:... |:.| |:.:.:|.|....|:
Human   189 KKTKTALLVPNALII---ATVTDRYIFVS-LLSR-DSTYKLLKSVCGHLENTSVGNSPNPSSAEN 248

  Fly   212 SFHERRKS----------TDLNMGVWAR--------NAGGQ-----NQR-----TVSMTVALQAN 248
            ||...|.|          :||:..|..|        ::|.|     |.|     |.|.||   .|
Human   249 SFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRVDFHATESQTV---LN 310

  Fly   249 VGPKTAKITETQTMRECSQPGQLYSIDVQSVNADIP-------------------YADTF--VVL 292
            |....||.|...........|:..|:.||.::..:.                   ||...  :::
Human   311 VSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALII 375

  Fly   293 MHFCLK---ATVEEHTDVLVFAEIQFLKSVWAVVKTF-IERNAYAGL--------EEFCQSLYSA 345
            ..|.::   .|:||...:|.           ::|.|. .|:.|.:||        |..||.| :|
Human   376 STFYMRYRINTLEEQLGLLT-----------SIVDTHNTEQAAPSGLRSQVQFNVEVLCQEL-TA 428

  Fly   346 LLIEIRKM 353
            .::::.|:
Human   429 NIVKLEKI 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30284	NP_726097.1	VASt	186..334	CDD:464975	42/215 (20%)
GRAMD2B	XP_011541895.1	PH-GRAM_GRAMDC	137..229	CDD:275406	24/101 (24%)