DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and Angptl1

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_082609.2	Gene:	Angptl1 / 72713	MGIID:	1919963	Length:	490	Species:	Mus musculus

Alignment Length:	208	Identity:	87/208 - (41%)
Similarity:	125/208 - (60%)	Gaps:	9/208 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 AGINSNGIHVIEVP---GLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGELSGE 132
            ||.:::||::|:..   ||  ..::|:..|...||||||:|.|||.||:|.||.|.:|||.:.||
Mouse   285 AGHSASGIYMIKPENSNGL--MQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGE 347

  Fly   133 FFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDSLRY 197
            :::||:.::.|:..:.|:|.:.:||::.....|.|..|.:...|..|.|. ||.|.|:||||:.:
Mouse   348 YWLGLDNIYKLSNQDNYKLMIELEDWSEKKVYAEYSSFRLEPESDYYRLR-LGTYQGNAGDSMMW 411

  Fly   198 HKGMPFSTFDHD-DTGHG-CARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSGRGITWMSWRGY 260
            |.|..|:|.|.| ||..| ||..:.|.|||:.|..|||||.:..||.:..|... ||.|..:||.
Mouse   412 HNGKQFTTLDRDKDTYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQD-GIFWAEYRGG 475

  Fly   261 DYGYKFVQMMIRP 273
            .|..:.|||||:|
Mouse   476 SYSLRAVQMMIKP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	87/208 (42%)
Angptl1	NP_082609.2	RILP-like	91..207	CDD:304877
Angptl1	NP_082609.2	FReD	274..489	CDD:238040	87/208 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3330
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43923
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810