DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and Angptl4

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_065606.2	Gene:	Angptl4 / 57875	MGIID:	1888999	Length:	410	Species:	Mus musculus

Alignment Length:	293	Identity:	86/293 - (29%)
Similarity:	138/293 - (47%)	Gaps:	43/293 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AQSNKLDLVYKKA---ESMVSSLKIRLEELKQSYKEITE---ERGSHETIN----PSSCLAAGIN 74
            ||::|:..:::|.   :..:|...:|::.|:.....:..   :.|..:|..    |......|:.
Mouse   115 AQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLAPTHLDNGVDKTSRGKRLPKMTQLIGLT 179

  Fly    75 SNGIHVIEVP----------------------GLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYR 117
            .|..|:...|                      |..||.|.|:....| ||||||||.:||.:|.:
Mouse   180 PNATHLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDG-GWTVIQRRLNGSVDFNQ 243

  Fly   118 CWEEYSQGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAI--GNASASYA 180
            .||.|..|||:..|||::||||:|.:|.....:|.|.::|::|   :|:...|.|  |....:|:
Mouse   244 SWEAYKDGFGDPQGEFWLGLEKMHSITGNRGSQLAVQLQDWDG---NAKLLQFPIHLGGEDTAYS 305

  Fly   181 LSVLGKYSGDAGDSLRYHKG--MPFSTFDHDDTGHG---CARIYVGAWWYDQCQRSNLNGQYLEG 240
            |.:....:.:.|.:.....|  :||||:|.|....|   ||:...|.||:..|..|||||||...
Mouse   306 LQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHS 370

  Fly   241 GRFEPKMSGRGITWMSWRGYDYGYKFVQMMIRP 273
            ...:.:...:||.|.:|:|..|..:...::|:|
Mouse   371 IPRQRQERKKGIFWKTWKGRYYPLQATTLLIQP 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	77/244 (32%)
Angptl4	NP_065606.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..101
		Fib_alpha	<104..133	CDD:285864	4/17 (24%)
		FReD	187..404	CDD:238040	73/221 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910