DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and angptl2b

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001119950.1	Gene:	angptl2b / 503514	ZFINID:	ZDB-GENE-050624-1	Length:	519	Species:	Danio rerio

Alignment Length:	230	Identity:	96/230 - (41%)
Similarity:	130/230 - (56%)	Gaps:	17/230 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GSHE---TINPS----SCLAA---GINSNGIHVIEVPGLEP-FPVYCDTRLAGSGWTVIQRRQDG 111
            |:|.   |..||    .||.|   |..::|:|:::...... ..|:||.|....||||||||.||
Zfish   287 GTHSPSTTNKPSGPWKDCLEALEDGHTNSGMHLVKPDNTNKLMQVWCDQRQDPGGWTVIQRRMDG 351

  Fly   112 SENFYRCWEEYSQGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNAS 176
            |.||:|.||.|.||||.:.||:::|||.::::|....|:|.|.:||::|....|.|..|.:...:
Zfish   352 SVNFFRNWETYKQGFGNIDGEYWLGLENIYWITNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEA 416

  Fly   177 ASYALSVLGKYSGDAGDSLRYHKGMPFSTFDHDD---TGHGCARIYVGAWWYDQCQRSNLNGQYL 238
            ..|.|.| |:|.|:|||||.:|.|..|:|.|.|.   ||: ||....|.|||:.|..|||||.:.
Zfish   417 DFYRLRV-GRYHGNAGDSLTWHNGKQFTTLDRDHDVYTGN-CAHYQKGGWWYNACAHSNLNGVWY 479

  Fly   239 EGGRFEPKMSGRGITWMSWRGYDYGYKFVQMMIRP 273
            .||.:..:... |:.|..:||..|..|.|.|||||
Zfish   480 RGGHYRSRYQD-GVYWAEFRGGAYSLKKVVMMIRP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	93/222 (42%)
angptl2b	NP_001119950.1	RILP-like	98..216	CDD:304877
angptl2b	NP_001119950.1	FReD	299..513	CDD:238040	89/216 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6515
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810