DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and Fga

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001008724.1	Gene:	Fga / 361969	RGDID:	2603	Length:	782	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	106/289 - (36%)
Similarity:	148/289 - (51%)	Gaps:	47/289 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AQSNKLDLVYKKAESMVSSLKIRLEELKQSYKE---ITEERGSHETI---------NPSSCLAAG 72
            :.|:|...|.|:   :..|.|:..|...::::|   .|.:||...|:         :||..
  Rat   502 SSSSKTSTVRKQ---VTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGA---- 559

  Fly    73 INSNGIHVIEVPGLEP-FPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGELS----GE 132
              .|||..|::||... |.||||...:..||.:||:|.|||.||.|.|::|.:|||.|:    ||
  Rat   560 --QNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGE 622

  Fly   133 FFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDSL-- 195
            |::|.:.||.||..... |.|.:||:.|....|.|. |.:|:.:..|||.| ..|.|.|||:|
  Rat   623 FWLGNDYLHLLTLRGSV-LRVELEDWAGKEAYAEYH-FRVGSEAEGYALQV-SSYQGTAGDALME 684

  Fly   196 -------RY--HKGMPFSTFDH--DDTGHGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSG 249
                   .|  |..|.|||||.  |.....||.:|.|.|||:.||.:||||.|..||.::|:.:.
  Rat   685 GSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNS 749

  Fly   250 -----RGITWMSWRGYDYGYKFVQMMIRP 273
                 .|:.|:.:||.||..:.|:|.|||
  Rat   750 PYEIENGVVWVPFRGADYSLRAVRMKIRP 778

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	94/243 (39%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..374
		Fibrinogen_aC	388..453	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..542		5/19 (26%)
		FReD	546..779	CDD:238040	94/242 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810