DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and tncb

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001299845.1	Gene:	tncb / 30037	ZFINID:	ZDB-GENE-980526-104	Length:	1811	Species:	Danio rerio

Alignment Length:	264	Identity:	96/264 - (36%)
Similarity:	141/264 - (53%)	Gaps:	31/264 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 STAQSNKLDLVY-KKAESMVSSLKIRLEELKQSYKEITEERGSHETINPSSCLAAGIN---SNGI 78
            ||..:.||..:. .|...::|::.:.:..|   ||            :|..|..|.:|   ::|:
Zfish  1558 STEYTVKLQAIAGPKRSRVISTVFLTIGVL---YK------------HPKDCSQALLNGDTTSGL 1607

  Fly    79 HVIEVPGLE--PFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGELSGEFFMGLEKLH 141
            :.|.:.|.|  |..||||....|.||.|..|||.|...|:|.|:.|:.|||:|:.||::||..||
Zfish  1608 YTIYLRGDESQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGLSNLH 1672

  Fly   142 FLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDSLRYHKGMPFSTF 206
            .:|:...|||.|.:.| .|....|:|:.|:|....|.|.:.| |.|||.||||:.||.|.||||:
Zfish  1673 KITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHV-GGYSGTAGDSMTYHHGRPFSTY 1735

  Fly   207 DHDD--TGHGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSGRGITWMSWRGYDYGYKFVQM 269
            |:|:  ....||..|.||:||..|.|.|:.|:|.:...      .:|:.|..|:|:::..:|.:|
Zfish  1736 DNDNDIAVTNCALSYKGAFWYKNCHRVNIMGRYGDNSH------SKGVNWFHWKGHEHSVEFAEM 1794

  Fly   270 MIRP 273
            .|||
Zfish  1795 KIRP 1798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	87/218 (40%)
tncb	NP_001299845.1	DnaJ	<471..>544	CDD:333066
		fn3	689..760	CDD:306538
		fn3	778..858	CDD:306538
		fn3	868..948	CDD:306538
		FN3	958..1047	CDD:238020
		fn3	1050..1128	CDD:306538
		fn3	1140..1215	CDD:306538
		fn3	1231..1303	CDD:306538
		fn3	1323..1400	CDD:306538
		fn3	1410..1482	CDD:306538
		fn3	1498..1570	CDD:306538	4/11 (36%)
		FReD	1589..1798	CDD:238040	86/228 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.710