Protein Alignment CG30281 and ANGPT2

DIOPT Version :10

• Sequence 1: NP_726164.1
• Gene: CG30281 / 246525
• FlyBaseID: FBgn0050281
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_001138.1
• Gene: ANGPT2 / 285
• HGNCID: 485
• Length: 496
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 92/282 - (32%)
• Similarity: 137/282 - (48%)
• Gaps: 18/282 - (6%)

  Fly     6 LCVLILSGGSLLS-------TAQSNKLDLVYKKAESMVSSLKIRLEELKQSYKEITEERGSHETI 63
            |.||:....|::.       ||..|. .::.|:...::.::...|..:..|...........|.|
Human   216 LQVLVSKQNSIIEELEKKIVTATVNN-SVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQI 279

  Fly    64 NPSSC---LAAGINSNGIHVIEVP-GLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQ 124
            :...|   ..:|..:|||:.:..| ..|....|||....|.|||:||||:|||.:|.|.|:||..
Human   280 SFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKV 344

  Fly   125 GFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSG 189
            |||..|||:::|.|.:..||..:.|.|.::::|:.|....:.||.|.:.:...:|.:.:.| .:|
Human   345 GFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKG-LTG 408

  Fly   190 DAGD-SLRYHKGMPFSTFDHDDTG--HGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSGRG 251
            .||. |.....|..|||.|.|:..  ..|:::..|.||:|.|..|||||.|....:...|.:  |
Human   409 TAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFN--G 471

  Fly   252 ITWMSWRGYDYGYKFVQMMIRP 273
            |.|..|:|..|..|...|||||
Human   472 IKWYYWKGSGYSLKATTMMIRP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	81/218 (37%)
ANGPT2	NP_001138.1	CCDC158	<78..>295	CDD:464943	14/79 (18%)
		FBG	280..494	CDD:214548	80/217 (37%)