Protein Alignment CG30281 and ANGPTL3

DIOPT Version :10

• Sequence 1: NP_726164.1
• Gene: CG30281 / 246525
• FlyBaseID: FBgn0050281
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_055310.1
• Gene: ANGPTL3 / 27329
• HGNCID: 491
• Length: 460
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 93/290 - (32%)
• Similarity: 142/290 - (48%)
• Gaps: 36/290 - (12%)

  Fly    16 LLSTAQSNKLDLVYKKAESMVSSLKIRLEELKQ-SYKEITE---------------------ERG 58
            ||.|.:..     ||:.....|.:|....:|:: |.:|.||                     ...
Human   178 LLQTVEDQ-----YKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNV 237

  Fly    59 SHETINPSSCLA---AGINSNGIHVIEVPGLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWE 120
            .|:.| |:.|..   .|.:::|::.|.....:.|.||||. ::||.||:||.|.|||:||...||
Human   238 KHDGI-PAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDV-ISGSPWTLIQHRIDGSQNFNETWE 300

  Fly   121 EYSQGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLG 185
            .|..|||.|.|||::||||::.:.....|.|.:.:||:....|...| .|.:||...:|.|.::.
Human   301 NYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEY-SFYLGNHETNYTLHLVA 364

  Fly   186 KYSGDAGDSLRYHKGMPFSTFDHDDTGH-GCARIYVGA-WWYDQCQRSNLNGQYLEGGRFEPKMS 248
             .:|:..:::..:|.:.|||:||...|| .|...|.|. ||:|:|..:||||:|.:.........
Human   365 -ITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPER 428

  Fly   249 GRGITWMSWRGYDYGYKFVQMMIRPKCSNN 278
            .||::|.|..|..|..|..:|:|.|..|.:
Human   429 RRGLSWKSQNGRLYSIKSTKMLIHPTDSES 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	78/215 (36%)
ANGPTL3	NP_055310.1	GumC	<81..>205	CDD:442439	8/31 (26%)
		FReD	243..453	CDD:238040	77/212 (36%)