DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and Fga

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001104518.1	Gene:	Fga / 14161	MGIID:	1316726	Length:	789	Species:	Mus musculus

Alignment Length:	286	Identity:	105/286 - (36%)
Similarity:	146/286 - (51%)	Gaps:	52/286 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AESMVSSLKIRLEELKQSYKEITEERGSH-----ETINPSSCLA----------------AGINS 75
            :.|..|::|   :::.::|| :.:|.||.     ||.|.....|                :|. .
Mouse   508 SSSKTSTVK---KQVTKTYK-MADEAGSEAHREGETRNTKRGRARARPTRDCDDVLQTQTSGA-Q 567

  Fly    76 NGIHVIEVPG-LEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGELS----GEFFM 135
            |||..|:.|| .:.|.||||...:..||.:||:|.|||.||.|.|::|.:|||.|:    |||::
Mouse   568 NGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWL 632

  Fly   136 GLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDSL----- 195
            |.:.||.||..... |.|.:||:.|....|.|. |.:|:.:..|||.| ..|.|.|||:|
Mouse   633 GNDYLHLLTLRGSV-LRVELEDWAGKEAYAEYH-FRVGSEAEGYALQV-SSYRGTAGDALVQGSV 694

  Fly   196 ----RY--HKGMPFSTFDH--DDTGHGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSG--- 249
                .|  |..|.|||||.  |.....||.:|.|.|||:.||.:||||.|..||.::|:.:.
Mouse   695 EEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYE 759

  Fly   250 --RGITWMSWRGYDYGYKFVQMMIRP 273
              .|:.|:.:||.||..:.|:|.|||
Mouse   760 IENGVVWVPFRGADYSLRAVRMKIRP 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	95/250 (38%)
Fga	NP_001104518.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..420
		Fibrinogen_aC	392..457	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..555		7/28 (25%)
		FReD	550..786	CDD:238040	93/240 (39%)
		Fib_alpha	51..190	CDD:285864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810