DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30281 and Angpt4

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_033771.1	Gene:	Angpt4 / 11602	MGIID:	1336887	Length:	509	Species:	Mus musculus

Alignment Length:	291	Identity:	99/291 - (34%)
Similarity:	148/291 - (50%)	Gaps:	41/291 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AQSNKLDLVYKKAESM-------VSSLKIRL-------EELKQSYKEITE---------ERGSH- 60
            ||.|.|....::..|:       :::||..|       ..|:|..:::||         .:..|
Mouse   220 AQLNSLQEKREQLHSLLGHQTGTLANLKHNLHALSSNSSSLQQQQQQLTEFVQRLVRIVAQDQHP 284

  Fly    61 ---ETINP--SSCL---AAGINSNGIHVI-EVPGLEPFPVYCDTRLAGSGWTVIQRRQDGSENFY 116
               :|..|  ..|.   .:|:|::|::.| |....:|..|:||....|.|||:||.|:|||.||.
Mouse   285 VSLKTPKPVFQDCAEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQ 349

  Fly   117 RCWEEYSQGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYAL 181
            |.||||.:|||.::.|.::|.|.:|.||:...|.|.|.:.|:.|.....:||:|.:|:....|:|
Mouse   350 RTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSL 414

  Fly   182 SVLGKYSGDAG--DSLRYHKGMPFST--FDHDDTGHGCARIYVGAWWYDQCQRSNLNGQYLEGGR 242
            || ...|..||  :||. .:|..|||  .|:|:....||::..|.||:|.|..|||||.|....:
Mouse   415 SV-NDSSSSAGRKNSLA-PQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYSVHQ 477

  Fly   243 FEPKMSGRGITWMSWRGYDYGYKFVQMMIRP 273
            ...|::  ||.|..:||..|.....:||:||
Mouse   478 HLHKIN--GIRWHYFRGPSYSLHGTRMMLRP 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	85/221 (38%)
Angpt4	NP_033771.1	BMFP	140..217	CDD:294701
		FReD	292..507	CDD:238040	85/219 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..436		7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910