DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30281 and tnr

DIOPT Version :9

Sequence 1:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_001107287.1	Gene:	tnr / 100135076	XenbaseID:	XB-GENE-948286	Length:	1350	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	103/290 - (35%)
Similarity:	149/290 - (51%)	Gaps:	39/290 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LVYKKAESMVSSL-------KIRLEELKQSYKE----ITEERGSHETIN-------------PSS 67
            |.||.|......|       .||||.|.:|.:.    ::.:.|...::.             |..
Frog  1068 LTYKSANESRKELIVDAEDTWIRLEGLLESTEYTVSILSVQNGERSSVTHTVFTTGGRVFSYPQD 1132

  Fly    68 C---LAAGINSNGIHVIEVPG--LEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFG 127
            |   :..|.|.:|::.|.:.|  .:..|||||......||.|.||||:|..:|:|.|.:|..|||
Frog  1133 CAQHMLNGDNQSGVYYIYINGDMSQSVPVYCDMATDAGGWIVFQRRQNGLTDFFRKWADYRVGFG 1197

  Fly   128 ELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAG 192
            .|..||::||:.||.:|:...|||.:.|.|....|: |.|..|.||:|.:.|.|.: |.::|.:|
Frog  1198 NLEDEFWLGLDTLHQVTSQGRYELRIDMRDGQEAVY-AYYNKFNIGDARSLYKLRI-GDFNGTSG 1260

  Fly   193 DSLRYHKGMPFSTFDHDD--TGHGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSGRGITWM 255
            |||.||:|.||||.|.|:  ....||..|.|||||..|.|:||||:|.|      ....:||.|.
Frog  1261 DSLTYHQGRPFSTKDRDNDVAVTNCASSYKGAWWYKNCHRTNLNGKYGE------SRHSQGINWY 1319

  Fly   256 SWRGYDYGYKFVQMMIRPKCSNNLRRQGMQ 285
            .|:|:::...||:|.:||.....::::.:|
Frog  1320 HWKGHEFSIPFVEMKMRPYNHRTMKKRSLQ 1349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30281	NP_726164.1	FReD	63..274	CDD:238040	89/230 (39%)
tnr	NP_001107287.1	EGF_alliinase	153..196	CDD:282688
		EGF_2	198..223	CDD:285248
		EGF_2	260..285	CDD:285248
		EGF_2	292..316	CDD:285248
		FN3	321..410	CDD:238020
		fn3	413..493	CDD:278470
		fn3	502..582	CDD:278470
		FN3	592..676	CDD:238020
		fn3	684..763	CDD:278470
		fn3	773..840	CDD:278470
		fn3	862..939	CDD:278470
		fn3	949..1018	CDD:278470
		FN3	1037..1122	CDD:238020	12/53 (23%)
		FReD	1129..1337	CDD:238040	88/215 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	182	1.000	Domainoid score	I3392
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9330
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910