DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30278 and SLCO5A1

DIOPT Version :9

Sequence 1:	NP_001286710.1	Gene:	CG30278 / 246523	FlyBaseID:	FBgn0050278	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_112220.2	Gene:	SLCO5A1 / 81796	HGNCID:	19046	Length:	848	Species:	Homo sapiens

Alignment Length:	159	Identity:	32/159 - (20%)
Similarity:	49/159 - (30%)	Gaps:	41/159 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CKKCFESTCGP------CIDYRVSPPAADLPEPQAEVVKAVIEPDGPVRQ----EINIRAECSKG 75
            |:.....|.|.      |:|..........|.|.|.      .|..|...    :.|.|.:.||.
Human    46 CRPSLSPTSGDANPAFGCVDSSGHQELKQGPNPLAP------SPSAPSTSAGLGDCNHRVDLSKT 104

  Fly    76 RPLLESDKDKLRCCTMCVAQEQN-----LHPNLCSAQCRPLKTYLHLNEWTKRPLPKPTYKHSVI 135
            ..:..:         :.:.||:.     |..:.|...|....|::       :.|....|..|||
Human   105 FSVSSA---------LAMLQERRCLYVVLTDSRCFLVCMCFLTFI-------QALMVSGYLSSVI 153

  Fly   136 LDNNTIVGRCFPMKFQLRRTKKNCLDCGN 164
                |.:.|.:.:|........:|.|.||
Human   154 ----TTIERRYSLKSSESGLLVSCFDIGN 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30278	NP_001286710.1	None
SLCO5A1	NP_112220.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91		10/50 (20%)
		OATP	129..734	CDD:281175	15/61 (25%)
		MFS	131..>531	CDD:119392	14/59 (24%)
		KAZAL_SLC21	551..605	CDD:238650
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	821..848
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900