Protein Alignment CG30274 and CKMT2

DIOPT Version :10

• Sequence 1: NP_726252.1
• Gene: CG30274 / 246521
• FlyBaseID: FBgn0050274
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001816.2
• Gene: CKMT2 / 1160
• HGNCID: 1996
• Length: 419
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 103/454 - (22%)
• Similarity: 168/454 - (37%)
• Gaps: 124/454 - (27%)

  Fly    53 KLLSGTTASALSHRKPLSASSLQLSVTSYLSRFLKRGVYDKIKRRQTRL-----------DHN-- 104
            |||:|..||.|     .:.....:..|.||   |.|.......|.|.||           .||
Human     7 KLLTGRNASLL-----FATMGTSVLTTGYL---LNRQKVCAEVREQPRLFPPSADYPDLRKHNNC 63

  Fly   105 LFDVLWPAM------RKTSKARHLEEDINCGI-------------IAPDFDVFVVFQEFLVPLLK 150
            :.:.|.||:      :.|.....|::.|..|:             :|.|.:.:.||.:...|::|
Human    64 MAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIK 128

  Fly   151 ----------DMHCLSIDADFKPQPRLAYFPMDNGERLNTAAFVFDDESQLVTRCLVEVSRNLDQ 205
                      ..|...:||.          .:..|:        ||:...|.:|  |...|::..
Human   129 LRHNGYDPRVMKHTTDLDAS----------KITQGQ--------FDEHYVLSSR--VRTGRSIRG 173

  Fly   206 LELPLNLTIGQLEQAERLMMSKIFTTHFADAIGETDSGNYYTMTELLEPDSE------------V 258
            |.||...|     :|||..:..:..|......|:. :|.||.::|:.|.|.:            |
Human   174 LSLPPACT-----RAERREVENVAITALEGLKGDL-AGRYYKLSEMTEQDQQRLIDDHFLFDKPV 232

  Fly   259 TMMLSSLGLMIPLLDTKDLVQAAESTAFNGALWPYGRGAFVNSANNMAVWLNCQEHLRIISTTSS 323
            :.:|:..|:      .:|              ||..||.:.|......:|:|.::|.|:|   |.
Human   233 SPLLTCAGM------ARD--------------WPDARGIWHNYDKTFLIWINEEDHTRVI---SM 274

  Fly   324 KEPADMGAAYTRVGRAITYLETQL-----HFKESYLLGYLQSRPSYLGTGLKMTTIVKLTNLMKE 383
            ::..:|...:.|..|.:..:|..:     .|..:..|||:.:.||.|||||:....|::..|.|:
Human   275 EKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKD 339

  Fly   384 ------MDNLRHLCSVRGLSMVTNRLSKLTVRLVNMQSMGVVEYVLFQDYCTAVTNILSLEKDM 441
                  ::|||  ...||...|..........:.|:..:|..|..|.|.....|..::..||.:
Human   340 PRFSKILENLR--LQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKL 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30274	NP_726252.1	phosphagen_kinases	75..440	CDD:470681	95/429 (22%)
CKMT2	NP_001816.2	Cardiolipin-binding. /evidence=ECO:0000250	40..64		6/23 (26%)
		creatine_kinase_like	50..407	CDD:153076	87/403 (22%)