Protein Alignment MFS1 and Slc17a6

DIOPT Version :9

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_445879.1
• Gene: Slc17a6 / 84487
• RGDID: 620531
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 147/508 - (28%)
• Similarity: 242/508 - (47%)
• Gaps: 48/508 - (9%)

  Fly    13 QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENTN------PNFPEYDWNEMERSYILSSFFW 71
            :|::...:..|...:::..:.|.|||:|.|.|....:      ....:::|:......|..||||
  Rat    69 RRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFW 133

  Fly    72 GYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWC--VSWGGWQAYCAI--RMSMGLFQGF 132
            |||:||..||::..|..|......:.:.::.|.:|||..  |.:|     |.|  |:..||.:|.
  Rat   134 GYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGV 193

  Fly   133 LFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLWC 197
            .:|..|...:.|.|..||:||...:..|...|.::||..:|:|...: ||..:|||....|::|.
  Rat   194 TYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMVWY 257

  Fly   198 IVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVT 262
            :.|.:.....|.:...|.:.|..|||.||..|...    |.|......||:..:||:|.:|::|.
  Rat   258 MFWLLVSYESPAKHPTITDEERRYIEESIGESANL----LGAMEKFKTPWRKFFTSMPVYAIIVA 318

  Fly   263 RCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITG 327
            ..|:||.:..|....|||...|...::....:.||:|:|...::..:...|||.|.::.|:|.|.
  Rat   319 NFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTT 383

  Fly   328 IRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAGILM 392
            :||.:|...|.:.|..|:.|.:  :..:.:|:..:...||.:..:..|..:|.:|::|.:|.|||
  Rat   384 VRKIMNCGGFGMEATLLLVVGY--SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILM 446

  Fly   393 GIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDAP-- 455
            ||.|....:..::.|::||.:.| :..||:||.||:|:|::...|.|.|..|.....|||..|
  Rat   447 GISNGVGTLSGMVCPIIVGAMTK-NKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADPEE 510

  Fly   456 -----------DFMDKQR---SSNLQEVGHSKALEA---------QGSEKVEE 485
                       |.:|::.   :.|....|.:|:..|         .|.||.||
  Rat   511 TSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEKKEE 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	130/435 (30%)
		2A0114euk	19..456	CDD:129972	135/459 (29%)
Slc17a6	NP_445879.1	2A0114euk	70..511	CDD:129972	136/453 (30%)
		MFS	75..498	CDD:119392	130/435 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820