DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS1 and PHT4;3

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001326351.1	Gene:	PHT4;3 / 823851	AraportID:	AT3G46980	Length:	581	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	130/461 - (28%)
Similarity:	224/461 - (48%)	Gaps:	41/461 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTAETNTGPMIGQRHLQTF-LLFLSIVVNYMAKFNAGVAVVAMTNAENTNPNFPEYDWNEMERSY 64
            :||:.|....|....::.. :|.|::.:....:....||:|.::.:..         |::.....
plant   145 LTAQPNFSEFITSERVKVVAMLALALALCNADRVVMSVAIVPLSLSRG---------WSKSFSGI 200

  Fly    65 ILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAIRMSMGLF 129
            :.|||.|||:::...||.|..|||.::.|.......:|...|.||......| |..|.|..:|:.
plant   201 VQSSFLWGYLISPIAGGTLVDRYGGKVVMAWGVALWSLATFLTPWAADSSLW-ALLAARAMVGVA 264

  Fly   130 QGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIF--YVSCGV 192
            :|...||::..:|.|.|..||:|...:|..|...|.:|.:..|.:|.:..    ||:  :|..|:
plant   265 EGVALPCMNNMVARWFPPTERSRAVGIAMAGFQLGNVVGLMLSPILMSQG----GIYGPFVIFGL 325

  Fly   193 -GVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELK--ATGPIPVPWKAIWTSV 254
             |.||.:||....::.|.....|.::||.||:    ..::....|.|  :|..|| |:..:.:.:
plant   326 SGFLWLLVWLSATSSAPDRHPQITKSELEYIK----QKKQISTMENKRISTSGIP-PFGRLLSKM 385

  Fly   255 PFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSW-VMAFVYLII---AD 315
            |.||::|.....|||:..:.:.||.|.|.|..:::|..|.:||:|    | :|||...|.   :|
plant   386 PTWAVIVANSMHSWGFFVILSWMPIYFNSVYHVNLKQAAWFSAVP----WSMMAFTGYIAGFWSD 446

  Fly   316 ILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINT 380
            :|:.|| .|||..||.:.||.|..|..||||::  ...|..:|...:...||:.:.|.:|..||.
plant   447 LLIRRG-TSITLTRKIMQSIGFIGPGIALIGLT--TAKQPLVASAWLSLAVGLKSFSHLGFLINL 508

  Fly   381 IDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVY--VA 443
            .:::|.::|:|.|:..||..:..|:..:..|..|:   ....:|...:::|:::.:..:.|  .|
plant   509 QEIAPEYSGVLHGMCLTAGTLAAIVGTVGAGFFVE---LLGSFQGFILLTAILYLLSALFYNIYA 570

  Fly   444 FGKMVN 449
            .|:.|:
plant   571 TGERVD 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	123/437 (28%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	126/443 (28%)
PHT4;3	NP_001326351.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920