DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and slc17a5

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	467	Identity:	150/467 - (32%)
Similarity:	233/467 - (49%)	Gaps:	48/467 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNA-----ENTNPNF----------------PEYDW 57
            |:....:..|...:.|..:.|..||:|.|.|:     |||..|.                .:|||
Frog    40 RYNLALMALLGFFMLYALRVNLSVALVDMVNSTSTPRENTTANICPDHTSAPAVLHNSTGQKYDW 104

  Fly    58 NEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYC-- 120
            :...:.:||.|||:||||||..||::..:.|.:..:....:|:|:..:|.|....:|   |.|
Frog   105 DANTQGWILGSFFYGYILTQIPGGYVAGKIGGKQLLGFGILGTAVFTLLTPLAADFG---AGCLI 166

  Fly   121 AIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGI 185
            |:|...||.:|..||.:||..|.|.|..||:||.:|:..|...||:|::..|||: ...:.|..:
Frog   167 AVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLSLSYAGAQLGTVVSLPVSGLI-CYYMDWIYV 230

  Fly   186 FYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSIN---SSRKAEEAELKATGPIPVPW 247
            ||:...:||||.|:|....::.|:..:.|.::|..||..::.   |.||:            ||.
Frog   231 FYIFGTLGVLWFIMWCFLVSDTPQSHRSITDSEKEYILYTLQNQLSYRKS------------VPC 283

  Fly   248 KAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLI 312
            .|:..|:|.||::|.....:|.:.||.|.:|.||..:|..:.:.|...||||||..||...:..:
Frog   284 CAMMKSLPLWAIIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQENGFLSALPYLGCWVFMIMAGV 348

  Fly   313 IADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGST 377
            |||.|..:..:|...:||..|::....||..|:...: .....:||||.:..:..:...|..|..
Frog   349 IADCLREKLNISTKVVRKIFNTLGMLGPAIFLLAAGY-TGCNYSLAVVFLTLSTTLGGFSVAGYG 412

  Fly   378 INTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDR--EQWQIVFIISAVIFCVGNIV 440
            ||.:|::|:.||:|:||.||.:.|..::.|::...:.   ||.  |||||||.|:|.|...|.|.
Frog   413 INHLDIAPSFAGLLLGITNTFATIPGMVGPVIAKALT---HDNTVEQWQIVFYIAAAINFFGAIF 474

  Fly   441 YVAFGKMVNQPW 452
            ::.|.....|.|
Frog   475 FIIFASGNVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	146/453 (32%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	149/462 (32%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	142/442 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000