DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS1 and slc17a7

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	504	Identity:	152/504 - (30%)
Similarity:	243/504 - (48%)	Gaps:	42/504 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENT----NP---NFPEYDWNEMERSYILSSFF 70
            :|::...:..|...:::..:.|.|||:|:|.| .||    |.   ...::.|:......|..|||
Frog    61 RRYIIAIMSGLGFCISFGIRCNLGVAIVSMVN-NNTVYKGNKIVIEQAQFTWDPETVGMIHGSFF 124

  Fly    71 WGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIP-------WCVSWGGWQAYCAIRMSMGL 128
            ||||:||..||::|:::.|......:.:.::.|.:|||       .||        ..:|:..||
Frog   125 WGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACV--------ICVRILQGL 181

  Fly   129 FQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVG 193
            .:|..:|..|...:.|.|..||:||...|..|...|.:|||..:|:|...| ||..:|||....|
Frog   182 VEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSVFYVYGSFG 245

  Fly   194 VLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEE--AELKATGPIPVPWKAIWTSVPF 256
            ::|.:.|.:.....|.....|.|.|..|||.||..|.....  |:.||      ||:..:||:|.
Frog   246 IMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKA------PWRKFFTSMPV 304

  Fly   257 WALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRG 321
            :|::|...|:||.:..|....|||...|...::....|.||||:|...::..:...|||.|.|:.
Frog   305 YAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQIADFLRTKR 369

  Fly   322 IMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPN 386
            |||.|.:||.:|...|.:.|..|:.|.:  :..:.:|:..:...||.:..:..|..:|.:|::|.
Frog   370 IMSTTNVRKMMNCGGFGMEATLLLVVGY--SHSRGVAISFLVLAVGFSGFAISGFNVNHLDIAPR 432

  Fly   387 HAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQP 451
            :|.|||||.|....:..::.||:||.:.| ...||:||.||:|::::...|.:.|..|.....||
Frog   433 YASILMGISNGVGTLSGMVCPLIVGAMTK-HKTREEWQYVFLIASLVHYGGVLFYGIFASGEKQP 496

  Fly   452 WDAPDFMDKQRSSNLQE-------VGHSKALEAQGSEKVEEAKRNESEG 493
            |..|:....::...:.|       ...|:|..|.||....:....::.|
Frog   497 WAEPEETSDEKCGFIHEDELADESEEQSQAYGAYGSYGATQTTSQQNGG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	139/441 (32%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	143/452 (32%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	145/459 (32%)
		MFS	67..490	CDD:119392	139/441 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547		6/29 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920