Protein Alignment MFS1 and Slc17a7

DIOPT Version :9

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_892038.2
• Gene: Slc17a7 / 72961
• MGIID: 1920211
• Length: 560
• Species: Mus musculus
• Alignment Length: 504
• Identity: 155/504 - (30%)
• Similarity: 249/504 - (49%)
• Gaps: 33/504 - (6%)

  Fly     1 MTAETNTGPMIG-------QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENTN------PNF 52
            :|..|...|::.       :|::...:..|...:::..:.|.|||:|:|.|...|:      ...
Mouse    42 VTTHTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQK 106

  Fly    53 PEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWC--VSWGG 115
            .:::|:......|..|||||||:||..||::|:::.|......:.:.::.|.:|||..  |.:|
Mouse   107 AQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYG- 170

  Fly   116 WQAYCAI--RMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAAS 178
                |.|  |:..||.:|..:|..|...:.|.|..||:||...|..|...|.:|||..:|:|...
Mouse   171 ----CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQY 231

  Fly   179 SIGWPGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPI 243
            | ||..:|||....|:.|.:.|.:.....|.....|.|.|..|||.:|..|.|......|    .
Mouse   232 S-GWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTK----F 291

  Fly   244 PVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAF 308
            ..||:..:||:|.:|::|...|:||.:..|....|||...|...::....|.||||:|...::..
Mouse   292 NTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVP 356

  Fly   309 VYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGST 373
            :...|||.|.:|.|||.|.:||.:|...|.:.|..|:.|.:  :..|.:|:..:...||.:..:.
Mouse   357 IGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAI 419

  Fly   374 IGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGN 438
            .|..:|.:|::|.:|.|||||.|....:..::.|::||.:.| ...||:||.||:|::::...|.
Mouse   420 SGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTK-HKTREEWQYVFLIASLVHYGGV 483

  Fly   439 IVYVAFGKMVNQPWDAPDFMDKQRSSNLQEVGHSKALEAQGSEKVEEAK 487
            |.|..|.....|||..|:.|.:::..   .|||.:...:..||..:||:
Mouse   484 IFYGVFASGEKQPWAEPEEMSEEKCG---FVGHDQLAGSDESEMEDEAE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	138/435 (32%)
		2A0114euk	19..456	CDD:129972	142/446 (32%)
Slc17a7	NP_892038.2	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	138/436 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		10/36 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838674
Domainoid	1	1.000	49	1.000	Domainoid score	I11710
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750