DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and CG7091

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	107/465 - (23%)
Similarity:	203/465 - (43%)	Gaps:	57/465 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AGVAVVAMTNAENT----------NPNFPE-----YDWNEMERSYILSSFFWGYILTQFMGGWLC 84
            ||::.:...|..:|          ||...|     ..|...:.......:::||:::..:.|:|.
  Fly    68 AGLSRLTEGNVTSTGRCGSPRVVFNPQIQETQSGDLPWTRNQELTFPGVYYYGYVVSISLSGYLA 132

  Fly    85 RRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAIRMSMGLFQGFLFPCIHAHLANWCPVKE 149
            .|..::....||.|..|:..:|:| .::...::|.....:..||..|...|.::.....|....|
  Fly   133 DRCSSKRLFIVSLIFEAVAYILLP-AMAHSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTE 196

  Fly   150 RNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGV----GVLWCIVWWIFGANQPRE 210
            |..|.:.|.:|:..|:::....:..|  |:.||...|||..||    |:..|.:.:......||
  Fly   197 RTALLSFAYSGLLMGSMLVYPVASYL--SNFGWELSFYVVGGVGLSFGIACCFLVYDTVEQHPR- 258

  Fly   211 SKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQT 275
               |...|::|:..  ..|:..::.:...|    :|||::..:.|.:|.::|....::.:..:..
  Fly   259 ---ISNEEVDYLRQ--GKSQLGQQRQPVVT----IPWKSLLAAPPVYAFILTHMFHTYTFLVIVQ 314

  Fly   276 EMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITG-----IRKSVNSI 335
            .||.:|...:..|::.....||.||| ..:.:.|..|:....:.|.:    |     :|:.:..|
  Fly   315 LMPRFMREAMEFDLREVGFLSAAPYL-GGICSKVMCILGGSYVERRV----GPDQNCVRRMLYGI 374

  Fly   336 AFFVPAAALIGVSFLDNTQKTLAVVLMCA------NVGINAGSTIGSTINTIDLSPNHAGILMGI 394
            ...: ..:||||..|.|....:.|::|.|      ::|.:     |.....:..:|:.||:|.|:
  Fly   375 CSIL-TTSLIGVIILANCDDKILVLVMFAFMMATTDMGFS-----GYWPTLLYFAPSFAGLLSGL 433

  Fly   395 VNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVN-QPWDAPDFM 458
            .|..:::...|.|.||..:|... .:::|.:| :::.::|....::..||....| ||||....|
  Fly   434 ANGMAHLSGFLAPHLVAALVHTG-SKDEWNVV-LMTLIVFNTMAMLVFAFCSSTNLQPWDPRSRM 496

  Fly   459 DKQRSSNLQE 468
            :|..|.:.||
  Fly   497 EKTASPSAQE 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	95/438 (22%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	102/451 (23%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	101/446 (23%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	88/392 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970