DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS1 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	146/551 - (26%)
Similarity:	236/551 - (42%)	Gaps:	110/551 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IGQRHLQT---FLLFLSIVVNYMAKFNAGVAVVAM-----------TNAENTN------------ 49
            :||...:|   ::.|:..:||||.:.|..:.:|.|           |:..:|:
  Fly     1 MGQVEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFS 65

  Fly    50 --------PNFP----EYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSAL 102
                    .|.|    .:.|||.::..:|.||||.:...|..||.|..:||.::....|......
  Fly    66 LERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVF 130

  Fly   103 LVVLIPWCVSWGGWQAYCAIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLV 167
            ...||| .||:..:.....:|:..|...|..:|.:|...|.|.|..||::
  Fly   131 CCFLIP-IVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSK--------------- 179

  Fly   168 AMFASGLLAASSIG----------------WPGIFYVSCG-VGVLWCIVWWIFGANQPRESKFIG 215
              |.|..| .||:|                |..::|: || ||.||.|.|.....:.|.|...|.
  Fly   180 --FVSAYL-GSSVGVALFYPIFGYIIDWTRWEWVYYI-CGIVGTLWFIAWQFLVFDSPAEHPRIA 240

  Fly   216 EAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAY 280
            ::|..:||.|:.:|.:..:.        |.|||||.||.|.|..:|.:....||..||.|..|.|
  Fly   241 DSERKFIEKSLGASIQGSKG--------PTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTY 297

  Fly   281 MNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITGIRKSVNSI-----AFFVP 340
            ...:...::::....|.||:|...:.|:|:.|.||.||....||.|.:||....|     ...|.
  Fly   298 FRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVL 362

  Fly   341 AAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPIL 405
            |.|..|.:      .|.|:||:.....::...:.|...:.:|||||:|||::|:......:...:
  Fly   363 ALAYFGYN------ATAAIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFI 421

  Fly   406 TPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDA-----PDFMDKQRSSN 465
            :|.:||.:..::...:.|:.||::::::.....|:||.|.:...|||::     ||...|:
  Fly   422 SPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFSESKLQPWNSGCHQLPDSGLKE---- 482

  Fly   466 LQEVGHSKALEAQGSEKVEEAKRNESEGIKD 496
            ||.:|..:       :..||.|..:|:..|:
  Fly   483 LQNLGRDQ-------DDEEEKKPLKSDHDKE 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	129/485 (27%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	132/498 (27%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	135/506 (27%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	117/417 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970