DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001009713.1	Gene:	Slc17a5 / 363103	RGDID:	1311388	Length:	495	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	137/465 - (29%)
Similarity:	229/465 - (49%)	Gaps:	36/465 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENT---------------------NPNFPEYDW 57
            |:....|.|....|.|..:.|..||:|.|.::.:|                     |....:|.|
  Rat    39 RYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLTDNRTSKECAEHSAPVKVHHNHTGKKYQW 103

  Fly    58 NEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAI 122
            :...:.:||.|||:|||:||..||::..|.|.::.:.:..:|:|:..:..|..... |..|...:
  Rat   104 DAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLGLGILGTAVFTLFTPLAADL-GVVALIVL 167

  Fly   123 RMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFY 187
            |...||.:|..||.:||..::|.|..||::|..::..|...||::::..||:: ...:.|..:||
  Rat   168 RALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGII-CYYMNWTYVFY 231

  Fly   188 VSCGVGVLWCIVW-WIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIW 251
            :...||::|.|:| ||. ::.|...|.|...|..||.:|:.:...:::.         |||.:|.
  Rat   232 LFGLVGIVWFILWMWIV-SDTPETHKTISHYEKEYIVSSLKNQLSSQKV---------VPWVSIL 286

  Fly   252 TSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADI 316
            .|:|.||::|.....:|.:.||.|.:|.||..:|..:::.|...|||||...|:...|....||.
  Rat   287 KSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMIVCGQAADY 351

  Fly   317 LLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTI 381
            |..:...|...:|:..:.|....||..|:...|: ....:|||..:..:..:...::.|.:||.:
  Rat   352 LRVKWNFSTISVRRIFSLIGMVGPAVFLVAAGFI-GCDYSLAVAFLTISTTLGGFASSGFSINHL 415

  Fly   382 DLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGK 446
            |::|::||||:||.||.:.|..::.|::...:..|:..:| ||.||.|:|.|...|.|.:..|.|
  Rat   416 DIAPSYAGILLGITNTFATIPGMIGPIIAKSLTPDNTIKE-WQTVFCIAAAINVFGAIFFTLFAK 479

  Fly   447 MVNQPWDAPD 456
            ...|.|...|
  Rat   480 GEVQNWALSD 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	131/447 (29%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	135/458 (29%)
Slc17a5	NP_001009713.1	2A0114euk	30..491	CDD:129972	137/465 (29%)
Slc17a5	NP_001009713.1	MFS	99..478	CDD:119392	120/392 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840