DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and CG3036

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	141/493 - (28%)
Similarity:	223/493 - (45%)	Gaps:	61/493 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAM-----TNAEN-------------TNPN--------F 52
            |.:...|..|..::||..:.|..:|:|.|     |:|.|             .:|:        |
  Fly    19 RQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERF 83

  Fly    53 PEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQ 117
            |   |:..:.:::|..||||||||:..||.|....|.|.....|.:.::||.::.| ..:...:.
  Fly    84 P---WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITP-LAAHINYV 144

  Fly   118 AYCAIRMSMGLFQGFLFPCIHAHLANWCPVKERNR---------LGALANTGIDCGTLVAMFASG 173
            ....:|:.:|...|..:|.||...|.|.|..||::         |||.....| ||.|:
  Fly   145 VLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSLGAAITMPI-CGYLI------ 202

  Fly   174 LLAASSIGWPGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELK 238
                |..||..:||::..||:||.:.|:.|....|.....|...|...||.:|.::...:.
  Fly   203 ----SVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKR---- 259

  Fly   239 ATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTS 303
               |..|||..:..|...||:::......:|:.|:..::|.:|:.:|..|:|.|.|:|:||||..
  Fly   260 ---PSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGK 321

  Fly   304 WVMAFVYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGI 368
            :|||.....:||.|..:|.:|.|..||...:.|..:|...:|...|| ....|.:|.:....:..
  Fly   322 YVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFL-GYDATWSVTIFSLALFA 385

  Fly   369 NAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVI 433
            :...|.|...|.:|::||..|.:.|:.||.|:....|:..:||.:...|.....|||||.|.|..
  Fly   386 HGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAAT 450

  Fly   434 FCVGNIVYVAFGKMVNQPWDAPDFMDKQRSSNL-QEVG 470
            :....:|:...|....|||:.|.  ::.|.|:: ||.|
  Fly   451 YISAAVVFAILGSGELQPWNNPP--ERVRISDVTQEEG 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	130/460 (28%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	134/471 (28%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	136/482 (28%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	118/400 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970