DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	489	Identity:	115/489 - (23%)
Similarity:	199/489 - (40%)	Gaps:	116/489 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TAETNTGPMIGQRHLQTFLLFLSIVVN--YMAKF----NAGVAVVA-MTNA-----ENTNPNFPE 54
            ||.....|.:.::.|....|.:|.::.  |:..|    |.|.|.|| ||.|     |..|
pombe    40 TASLKIDPKVEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLN----- 99

  Fly    55 YDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGA-RITMFVSTIGSALLVVLIPWCVSWGGWQA 118
                     ..:|.|:..|||.:.....|.:|..| |:..|:|...| :.|:...:..|:||
pombe   100 ---------VAVSIFYVLYILVETPSVVLVKRIKASRMLAFISFAWS-MTVLFSGFMSSYGG--- 151

  Fly   119 YCAIRMSMGLFQGFLFPCIHAHLANWCPVKER-NRLGAL-ANTGIDCGTLVAMFASGL---LAAS 178
            ..|.|:.:||.:|.|||.::.:|......||: .||..| |:.|: .|....:||..|   .|.:
pombe   152 LIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGL-AGAFGGLFAYALEQVHAGN 215

  Fly   179 SIGWPGIFYVS---CGVGVLWCI---------VWWIFGANQPRESKFIGEAELNYIETSINSSRK 231
            ..||..|:.|.   ..:||..|:         .|::     .||     |.|:..|...||:...
pombe   216 KEGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWFL-----TRE-----EREVAIIRRDINARYH 270

  Fly   232 AEE----AELKATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSN 292
            .|:    :|::.....|..:  :..:..|.|.||.     :|:|:.   :|..:.|:..:.:::|
pombe   271 GEQHFEWSEVRKAFKDPKVY--VSATSQFCADMVL-----YGFSSF---LPVIIKGLGFVGLQTN 325

  Fly   293 ALYSALPYLTSWVMAFVYLI-IADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFL------ 350
              |..:|...:.|::|:::. ::|....|.:              :.:.|:.::.|.::
pombe   326 --YMTIPVYIAGVISFLFVAWLSDRTQLRAV--------------YLISASTVVAVGYIIMLASD 374

  Fly   351 DNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAG-----ILMGIVNTASNIVPILTPLLV 410
            .|..|..|..:      |..|..||..:|...|:.|.||     ..:||..|.:|    .:.::.
pombe   375 SNAAKYTATYI------IAIGCYIGPGLNLGWLNNNVAGHYKRATAIGIQQTLAN----SSGIVA 429

  Fly   411 GIIVKDDHDREQWQI--VFIISAVIFCVGNIVYV 442
            |.|.: ..:..::.:  .|.:..||  ||.:.||
pombe   430 GQIYR-SKNAPKYILGNAFTLGCVI--VGGLAYV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	111/473 (23%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	111/472 (24%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	109/461 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050