DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS1 and liz1

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001342731.1	Gene:	liz1 / 2540342	PomBaseID:	SPBC2G2.01c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	489	Identity:	100/489 - (20%)
Similarity:	173/489 - (35%)	Gaps:	114/489 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAI 122
            ||::...::  |..|||:.|..|.:..:|..||:...|..|...|:.:   :..:....:|...:
pombe    67 NELQDINVV--FTCGYIIGQLPGSYALQRVPARLWFSVMNILWGLMTI---FSFAVHSVRALMIL 126

  Fly   123 RMSMGLFQGFLFPCIHAHLANWCPVKER-NRLGALANTGIDCGTLVAMFASGLLAA--SSI---- 180
            |..|.:.:...|...|..|..|....|. .|.|..:.:|: .||   |||..|..|  ||:
pombe   127 RFFMAVAEASTFAGTHYILGAWYKESELCKRAGIFSASGL-VGT---MFAGYLQTAVHSSLNGKG 187

  Fly   181 ---GWPGIFYVSCGVGVLWCIVWWIFG----ANQPRESK--FIGEAELNYIETSINSSRKAEEAE 236
               ||..:|.:.   |:| .|...::|    .:.|..:|  :..|.|.......:.:..|.:...
pombe   188 GLSGWRWLFIID---GIL-TIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRLPARPKKKPLT 248

  Fly   237 LKATGPIPVPWKAIWTSVPFW-------ALMVTRCCQSW-----GYSTLQ-TEMPAYMNGV-LLM 287
            |||...|...|: |:.....|       |:.|......|     .:|..| ...|..:..| ::.
pombe   249 LKAIKDIVRSWR-IYGLCILWIFSGETQAIAVNVLMGQWMKWSNKFSVAQINNYPTVITAVGVVS 312

  Fly   288 DMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDN 352
            .:.::.:...|.....|.......:|..:..|  |:....:.......|:|.......|
pombe   313 TLGASVISDKLAGNPRWPFGLFLCVITTVSAT--ILLAWNVPDGAKFFAYFASGCTYAG------ 369

  Fly   353 TQKTLAVVLMCANVGINAGSTIGSTINTIDL---SPNHAGILMGIVNTASNI-----VPILTPL- 408
                .||....||                |:   :....|:::.::|...||     .||:.|.
pombe   370 ----QAVWFSWAN----------------DICRDNDQERGVVVFLMNMCQNIWHIWWAPIMYPNT 414

  Fly   409 --------LVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDAPDFMD---KQR 462
                    |:|::|...       |||:.|    |:.:.:.:...::.....||.||.|   :..
pombe   415 DTPRFIKGLIGLLVVGG-------IVFVSS----CIVSYMQIRDKRIKRSIQDAKDFDDVFTEHE 468

  Fly   463 SSNLQEVGHSKALEAQGSEKVEEAKRNESEGIKD 496
            |..|:::|           |.:|...|.:..:|:
pombe   469 SLELKKIG-----------KNDEESLNTTNAVKE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	88/432 (20%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	90/444 (20%)
liz1	NP_001342731.1	MFS_1	37..401	CDD:311564	75/375 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050