DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and SPBC1773.15

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_595130.1	Gene:	SPBC1773.15 / 2539757	PomBaseID:	SPBC1773.15	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	484	Identity:	90/484 - (18%)
Similarity:	178/484 - (36%)	Gaps:	150/484 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLFLSIVVNYMAKFNAGVAVVAMTNAENTNPNFPEYDWNEMERSYILSSFFWGYILTQFMGGWLC 84
            ||.|.....||.|..:..:.: |....:.|....:|:|       :.:||:.|:::.......|.
pombe    55 LLCLISAFQYMDKSTSNYSSI-MGIRTDLNMVGNQYNW-------VGTSFYLGFMVFSLPLSTLL 111

  Fly    85 RRYGARITMFVSTIGSALLVVLIPWCVSWG----------GWQAYCAIRMSMGLFQGFLFPCIHA 139
            :::.      :|.:.||.:       |:||          .:.:|.|.|..:|:.:..:.|....
pombe   112 QKFP------LSKVTSAFI-------VAWGILMTLTCLVHSYASYIATRTLLGILESVITPAFVL 163

  Fly   140 HLANWCPVKER----------NRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGV 194
            .:|.|...:|:          |.||.|....:..|.......:.|..:.   |..:|.::..:.:
pombe   164 FIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSYGLYKRELENNLTMSP---WRILFIITGLITI 225

  Fly   195 LWCIVWWIFGANQPRESKFIGEAELNYIETSINS------SRKAEEAE-LKATGPIPVP---WKA 249
            :..:..:|...::|.::.|:.|.|.:.:...:::      |:|.::.: |:|...:.:.   :..
pombe   226 INGVFIFIHIPDEPSKAWFLSEKEKDLVLKRLDTDHAGLGSKKFKKYQILEACRDVRMYLYFFLQ 290

  Fly   250 IWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNG-VLLMDMKSNA-------LYSALPYLTSWVM 306
            |..::|...|.        .:|::..:...|:.| .|||:|.:::       |:..:|..|:..|
pombe   291 IAVAIPNGGLS--------NFSSIMLKNLGYVKGKALLMNMPTSSISFAALTLFGLIPEFTNRRM 347

  Fly   307 AFVYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAA------LIGVSFLDNTQKTLAVVLMCAN 365
                    ||.|....:::|    |.:.|||..|..|      |.|:|.:     ....:|.|
pombe   348 --------DIALVGLAINLT----SGSLIAFAKPTHAQLAGYWLFGISPI-----PYICILSC-- 393

  Fly   366 VGINAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFI-- 428
                             :|.|.||                            |.::    ||:
pombe   394 -----------------ISSNSAG----------------------------HTKK----VFMSA 409

  Fly   429 ISAVIFCVGNIVYVAFGKMVNQPWDAPDF 457
            :|.:.:||||:|    |....:...||.:
pombe   410 VSMIGYCVGNMV----GPQTFRSTQAPKY 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	87/469 (19%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	89/481 (19%)
SPBC1773.15	NP_595130.1	MFS	55..426	CDD:119392	88/474 (19%)
SPBC1773.15	NP_595130.1	2A0114	58..445	CDD:273326	88/481 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050