DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and SPCPB1C11.03

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001342988.1	Gene:	SPCPB1C11.03 / 2539453	PomBaseID:	SPCPB1C11.03	Length:	570	Species:	Schizosaccharomyces pombe

Alignment Length:	460	Identity:	89/460 - (19%)
Similarity:	171/460 - (37%)	Gaps:	114/460 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 FFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWC--VSWGGWQAYCAIRMSMGLFQG 131
            |:.|||:.||.|.::.:.:  .:..||..:..:..|::...|  .::||   ..|:|..:|..:.
pombe   146 FYVGYIVGQFPGHYIMQTF--PLGKFVGLVTFSWSVIVFLHCCAYNYGG---LIALRFFLGFTES 205

  Fly   132 FLFPCIHAHLANWCPVKERNRLGALA-NTGIDCGTLVAMFASGL--LAASSIGWPGIFYVSCGVG 193
            .|.|.:.|.:..:...:|:..|..:. .:.:.||......|.||  :..|...|.....::.|:.
pombe   206 CLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCGIPAGFIAYGLEFVTKSIAPWKLFMIITGGIT 270

  Fly   194 VLWCIVWWIFGANQPRESKFIGEAELNY------------IETSINSSRKAEEAELKATGPIPVP 246
            ....|..:.:..:.|.:::|:.:.|..|            ||..|....:..|| ||.    |:.
pombe   271 FFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEA-LKD----PIT 330

  Fly   247 WKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYL 311
            |  ::|...|..::....              ||...::...:..:.|.|.|    ..|....|.
pombe   331 W--LFTFAAFTLMLSNNL--------------AYQQNLIFTSLNVSDLNSTL----VGVALAGYN 375

  Fly   312 IIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFL----DNTQKTLAVVLMCANVGIN--- 369
            .::.|:.|..:..|.  .:|.....|::..:...|::|:    .|....||.:::.::.||.
pombe   376 TVSAIIATFAMYLIP--NQSAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIASDFGITYII 438

  Fly   370 --AGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQ-------- 424
              ..:|..||..|..|:..    ||.:|..|  |..|::|.|             ||
pombe   439 ALGWTTATSTGYTKKLTRG----LMFMVGYA--IANIISPQL-------------WQSRDAPRYY 484

  Fly   425 --------IVFIISAVIFCVGNIVYVAFGKMVNQPWDAPDFMDKQRSSNLQEVGHSKALEAQGS- 480
                    :.:.::.:|:.|..::..                  :|:...:|:...|.  |:||
pombe   485 PAWIVQIVVAWFVTPIIYLVARVILA------------------RRNKQRKELKDKKI--AEGSL 529

  Fly   481 EKVEE 485
            |.:|:
pombe   530 ETIEK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	81/416 (19%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	81/428 (19%)
SPCPB1C11.03	NP_001342988.1	UhpC	102..494	CDD:332119	79/398 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050