DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and SPCC417.10

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_588287.1	Gene:	SPCC417.10 / 2539419	PomBaseID:	SPCC417.10	Length:	508	Species:	Schizosaccharomyces pombe

Alignment Length:	532	Identity:	106/532 - (19%)
Similarity:	188/532 - (35%)	Gaps:	156/532 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLFLSIVVNYMAKFNAGVAVVAMTNAENTNPNFPEYDWNEMERSYILSSFFWGYILTQFMGGWLC 84
            ::.|...:.::.|.:...||: |...|:.......|.|:.       ::|:.||::.:|....|.
pombe    68 VMCLVYCIQFLDKTSNSYAVI-MGLKEDLKMEGQMYSWSG-------TAFYLGYLVFEFPASLLL 124

  Fly    85 RRYGARITMFVSTIGSALLVVLIPW----CV-SWGGWQAYCAIRMSMGLFQGFLFPCIHAHLANW 144
            :|:         .:...|.|.|:.|    |: |...:..:.|:|:.:|:.:....|......|.|
pombe   125 QRF---------PLSKTLCVFLVIWGFLLCMTSVANYPGFIALRVLLGMMESAASPGFILLTAQW 180

  Fly   145 CPVKER----------NRLGALANTGIDCGTLVAMFASGLLAASSI---GWPGIFYVSCGVGVLW 196
            ....|:          |.||.:         |.:..|.||...:|:   ||..||.: |||..:
pombe   181 YKRSEQQLRTSVWVAFNGLGQI---------LGSCMAYGLAKRTSLPMRGWKLIFII-CGVLAI- 234

  Fly   197 CIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMV 261
                            |:|...|..:..:                    |:||.:.:.....|:|
pombe   235 ----------------FLGFVILAVVPDN--------------------PFKAWFLTEEDRKLVV 263

  Fly   262 TRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADI---------- 316
            .|             :.|...||.....|.......:..:.:|:| ||..::.:|
pombe   264 KR-------------LRANKQGVGNNHFKLYQFKETMLDIRTWIM-FVSSVLLNIPNGGIGTFSS 314

  Fly   317 LLTRGIMSITGIRKSVNSIAFFVPAAA-----LIGVSFLD---NTQKTLAVVLMCANVGINAGST 373
            ||.:|.|..    .::.::...:||.|     ||...||.   :.:..||.:..|.       :.
pombe   315 LLIKGTMGY----DTLQTLLMGLPAGACEFGGLIAFGFLSLFIHKRMVLATITTCI-------AL 368

  Fly   374 IGSTINTIDLSPNH--AGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCV 436
            |||.:.:....|..  ||..:.:|:..:.||      :..||..:.....:...|.:|..:.:||
pombe   369 IGSCLLSFAGPPRAQLAGYYLLMVSPGAMIV------MFAIISSNASGYTKKVTVGVIYLIGYCV 427

  Fly   437 GNIVYVAFGKMVNQPWDAPDFMDKQRSS-----------------NLQEVGHSKALEAQGSEKVE 484
            ||::    |....:..|||::|..:.:.                 |.:|......|.|:|  |:|
pombe   428 GNLI----GPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYYVNWRENKRRDQLAAEG--KIE 486

  Fly   485 EAKRNESEGIKD 496
            .....|.|.:.|
pombe   487 HRPNAEFEDLTD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	91/461 (20%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	94/473 (20%)
SPCC417.10	NP_588287.1	MFS	66..436	CDD:119392	92/466 (20%)
SPCC417.10	NP_588287.1	2A0114	71..468	CDD:273326	96/495 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050