DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and slc-17.8

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001023848.1	Gene:	slc-17.8 / 179234	WormBaseID:	WBGene00017798	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	491	Identity:	136/491 - (27%)
Similarity:	226/491 - (46%)	Gaps:	41/491 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENT--NPNFPE-----YDWNEMERSYILSSFFW 71
            |.:.:.:|.......::...|.|:|:|.|.|:..|  |..:||     .||:..|:.||.|:|..
Worm    53 RFMTSIMLCFCFGCVHLMNSNMGMAIVCMVNSSATYDNETYPENAAPLLDWSSDEQGYIFSAFNA 117

  Fly    72 GYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAI--RMSMGLFQGFLF 134
            |.::..|.|| :..::.|:..:.||...::|....:||...   ...|.||  |..:|.....|.
Worm   118 GLLVMLFTGG-MADKFNAKYMILVSVAIASLANFTLPWMAP---ISVYWAIFSRFLVGFADALLQ 178

  Fly   135 PCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSI---GWPGIFYVSCGVGVLW 196
            |.:::.:..|.|..||:....||..|...|||:.:.|:|.|.:.:.   |||.|||:|..:|||:
Worm   179 PAMNSLITRWFPTSERSYALGLATGGRQIGTLIIIPAAGALCSQTEIFGGWPSIFYLSGFIGVLF 243

  Fly   197 CIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMV 261
            ...:...||::|.:...|.:.||.:    |..|.::|:...|.| ...||||.|..|...||.::
Worm   244 IFSYIFLGADKPSKQSCISDNELKF----ITISNQSEDVGKKRT-ERKVPWKNILKSGAVWASVI 303

  Fly   262 TRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSIT 326
            :..|..:...||...:|:|::.|.......|.:.||||.::.|     :..|....|...:...|
Worm   304 SLVCHEFPLMTLIMFLPSYLHDVHHYHSTENGILSALPTVSLW-----FAKIGSSYLNTWLQKNT 363

  Fly   327 -----GIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPN 386
                 .|.|.:|||........|:..:||||....:||:.:|.::......|.|..:..:.::|.
Worm   364 TWKKDTICKVLNSIGSIGLGVFLLAATFLDNEHAWMAVLFLCLSMASAGLHTPGCQLALVSVAPA 428

  Fly   387 HAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQP 451
            ::|.:.|.......:..|:.|::..:||| |....:|.:||.||.||.....|::..:|....|.
Worm   429 YSGAVTGFTFFFVAVSGIIHPIITKMIVK-DRTAAEWNLVFYISTVIAIFPIIIFNVWGSTEVQW 492

  Fly   452 WDAPDFMDKQRSSNLQEVGH---SKALEAQGSEKVE 484
            |      .|.::|..||..:   ||:.:|..|..::
Worm   493 W------AKSKASMQQEPNNKKMSKSSKASSSPSID 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	124/442 (28%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	127/453 (28%)
slc-17.8	NP_001023848.1	MFS_SLC17	57..486	CDD:340876	124/443 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030