DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and M117.1

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_502234.2	Gene:	M117.1 / 178112	WormBaseID:	WBGene00010918	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	510	Identity:	107/510 - (20%)
Similarity:	198/510 - (38%)	Gaps:	119/510 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NTGPM---------------IGQRHLQTFLLF------LSIVVN----------YMAKFNAGVAV 39
            ||.|:               :..:|...:::|      |..|:|          ||.| |:.:|.
Worm    50 NTSPILLGNLEMRCHRFRWNLSMKHRIRWVIFILTWLQLGSVMNCVDVFSFSMVYMEK-NSTIAA 113

  Fly    40 VAMTNAENTNPNFPEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLV 104
            .|..:        ..|.:...|:|.::|:...|.::..:....|.::||.|:.:..:::..|::.
Worm   114 EAGLD--------DIYIYTLEEKSSLISAMAIGSLIGMYPQNVLMQKYGPRLVLTFASLLCAVVT 170

  Fly   105 VLIPWCVSWGGWQAYCAIRMSMGLFQGFL----FPCIHAHLANWCPVKERNRLGALANTGIDCGT 165
            ..:||.:     .....:.:...:|||.|    |..:....:.|.|:||.. :...|.:|.....
Worm   171 AFMPWAL-----DTNYHVALVFRIFQGILYSADFGVVGYVCSKWSPIKEVG-MSLAALSGFTAAR 229

  Fly   166 LVAMFASGLLAASSIGWPGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYI--ETSINS 228
            .|..........|::||..|:|:...:..:..|:|::|..:.|.:...:...||.:|  .|..:.
Worm   230 AVIQLPLAGWTTSNVGWRPIYYILSIILFISTIIWFLFYRDDPEDHCLMTHHELQHIGGGTKRDK 294

  Fly   229 SRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGV-----LLMD 288
            ::|             .|::.:.|....||:.|.      |::.:.......:.|.     |.||
Worm   295 TKK-------------TPYREVLTDKSVWAVWVA------GFADIFASFVFLVYGAQYYQYLGMD 340

  Fly   289 MKSNALYSALPYLTSWVMAFV-YLIIADILLTRGIMSITGI---------RKS----VNSIAFFV 339
            :::||          |:.:.. ||.|       |:....||         .||    .|:|:..|
Worm   341 IQANA----------WLNSMKGYLFI-------GVRVFAGIASDRIRTLPEKSKLRLFNTISLQV 388

  Fly   340 PAAALIGVSFLDNTQKTLAVVLMC---ANVGINAGSTI-GSTINTIDLSPNHAGILMGIVNTASN 400
            ||..|:.|..|......|.|:.:.   |:.|.|.|... |:.:    :|...:..::|.:....:
Worm   389 PAFFLMLVVLLPREHPYLHVICITFYQASFGFNCGGFYKGAAL----ISRQFSYFVIGYIQLFKS 449

  Fly   401 IVPILTPLLVGIIV-KDDHDRE-QWQIVFIISAVIFCVGNIVYVAFGKMVNQPWD 453
            :..:|.|:|..::| ....|.| .|...|:|.|:...|.|.|||...:  ::|.|
Worm   450 LATLLEPVLFSLLVLPGSEDSELSWTSYFLIHALTLTVANTVYVLLAR--SEPAD 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	101/472 (21%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	103/482 (21%)
M117.1	NP_502234.2	2A0114euk	66..499	CDD:129972	102/489 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820