DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	116/456 - (25%)
Similarity:	209/456 - (45%)	Gaps:	38/456 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LQTFLLFLSIVVNYMA-KFNAGVAVVAMTNAEN-------------TNPNFPEYDWNEMERSYIL 66
            |...|.|.:||:  || :....:.:|||.|...             .|...|.:.|:...:..||
  Rat    20 LAILLHFCNIVI--MAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLIL 82

  Fly    67 SSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAIRMSMGLFQG 131
            ||.|.|.::.|...|:|...|..:..:..|...|::|.:|||.....|. ......|:..|:.||
  Rat    83 SSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGA-ALVIVCRVLQGIAQG 146

  Fly   132 FLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLW 196
            .:....|.....|.|..||.||.::..:|...|..:|:..||.: ...:|||.:||:...||.:.
  Rat   147 AVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFI-CDLLGWPMVFYIFGIVGCVL 210

  Fly   197 CIVWWIFGANQPRESKFIGEAELNYIETS----INSSRKAEEAELKATGPIPVPWKAIWTSVPFW 257
            .:.|:|...:.|....::..:|.:||.:|    ::|.|::            :|.||:..|:|.|
  Rat   211 SLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQS------------LPIKAMLKSLPLW 263

  Fly   258 ALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGI 322
            |:::......|..:.|.|..|.:::..|.::::.|.|.|:||||.:::...|...::|.||:|.|
  Rat   264 AIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKI 328

  Fly   323 MSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNH 387
            .|:..:||...::..|.|...::.:.:|.....:..:.|..||..::. |..|..||.:|::|.:
  Rat   329 FSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSF-SFCGQLINALDIAPRY 392

  Fly   388 AGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAV-IFCVGNIVYVAFGKMVNQP 451
            .|.|..:.........:::..|.|:|:..|.:....:..|:::.: :.|:.  .|:.|.|...|.
  Rat   393 YGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLA--FYLLFAKGDIQD 455

  Fly   452 W 452
            |
  Rat   456 W 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	111/444 (25%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	115/453 (25%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	116/456 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910