Protein Alignment MFS1 and Slc17a6

DIOPT Version :10

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_543129.3
• Gene: Slc17a6 / 140919
• MGIID: 2156052
• Length: 582
• Species: Mus musculus
• Alignment Length: 519
• Identity: 150/519 - (28%)
• Similarity: 247/519 - (47%)
• Gaps: 51/519 - (9%)

  Fly    13 QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENTN------PNFPEYDWNEMERSYILSSFFW 71
            :|::...:..|...:::..:.|.|||:|.|.|....:      ....:::|:......|..||||
Mouse    69 RRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFW 133

  Fly    72 GYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWC--VSWGGWQAYCAI--RMSMGLFQGF 132
            |||:||..||::..|..|......:.:.::.|.:|||..  |.:|     |.|  |:..||.:|.
Mouse   134 GYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGV 193

  Fly   133 LFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLWC 197
            .:|..|...:.|.|..||:||...:..|...|.::||..:|:|...: ||..:|||....|::|.
Mouse   194 TYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMVWY 257

  Fly   198 IVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVT 262
            :.|.:.....|.:...|.:.|..|||.||..|...    |.|......||:..:||:|.:|::|.
Mouse   258 MFWLLVSYESPAKHPTITDEERRYIEESIGESANL----LGAMEKFKTPWRKFFTSMPVYAIIVA 318

  Fly   263 RCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITG 327
            ..|:||.:..|....|||...|...::....:.||:|:|...::..:...|||.|.::.|:|.|.
Mouse   319 NFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTT 383

  Fly   328 IRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAGILM 392
            :||.:|...|.:.|..|:.|.:  :..:.:|:..:...||.:..:..|..:|.:|::|.:|.|||
Mouse   384 VRKIMNCGGFGMEATLLLVVGY--SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILM 446

  Fly   393 GIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDAP-- 455
            ||.|....:..::.|::||.:.| :..||:||.||:|:|::...|.|.|..|.....|||..|
Mouse   447 GISNGVGTLSGMVCPIIVGAMTK-NKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADPEE 510

  Fly   456 -----------DFMDKQR---SSNLQEVGHSKALEA---------QGSEKVEEAKRNESEGIKD 496
                       |.:|::.   :.|....|.:|:..|         .|.||.||..:   ||.:|
Mouse   511 TSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEKKEEFVQ---EGAQD 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS_SLC17	18..445	CDD:340876	130/436 (30%)
Slc17a6	NP_543129.3	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	130/436 (30%)