Protein Alignment MFS1 and Slc17a7

DIOPT Version :10

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_038966881.1
• Gene: Slc17a7 / 116638
• RGDID: 620101
• Length: 585
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 155/529 - (29%)
• Similarity: 249/529 - (47%)
• Gaps: 58/529 - (10%)

  Fly     1 MTAETNTGPMIG-------QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENTN--------- 49
            :|..|...|::.       :|::...:..|...:::..:.|.|||:|:|.|...|:
  Rat    42 VTTHTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQT 106

  Fly    50 ------------PNF----------PEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARIT 92
                        |..          .:::|:......|..|||||||:||..||::|:::.|...
  Rat   107 PYRSVHKQEAVTPTVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRV 171

  Fly    93 MFVSTIGSALLVVLIPWC--VSWGGWQAYCAI--RMSMGLFQGFLFPCIHAHLANWCPVKERNRL 153
            ...:.:.::.|.:|||..  |.:|     |.|  |:..||.:|..:|..|...:.|.|..||:||
  Rat   172 FGFAIVATSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRL 231

  Fly   154 GALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAE 218
            ...|..|...|.:|||..:|:|...| ||..:|||....|:.|.:.|.:.....|.....|.|.|
  Rat   232 ATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEE 295

  Fly   219 LNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNG 283
            ..|||.:|..|.|......|    ...||:..:||:|.:|::|...|:||.:..|....|||...
  Rat   296 RKYIEDAIGESAKLMNPVTK----FNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEE 356

  Fly   284 VLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVS 348
            |...::....|.||||:|...::..:...|||.|.:|.|||.|.:||.:|...|.:.|..|:.|.
  Rat   357 VFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVG 421

  Fly   349 FLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGII 413
            :  :..|.:|:..:...||.:..:..|..:|.:|::|.:|.|||||.|....:..::.|::||.:
  Rat   422 Y--SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAM 484

  Fly   414 VKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDAPDFMDKQRSSNLQEVGHSKALEAQ 478
            .| ...||:||.||:|::::...|.|.|..|.....|||..|:.|.:::..   .|||.:...:.
  Rat   485 TK-HKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCG---FVGHDQLAGSD 545

  Fly   479 GSEKVEEAK 487
            .||..:|.:
  Rat   546 ESEMEDEVE 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS_SLC17	18..445	CDD:340876	139/461 (30%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	139/461 (30%)