Protein Alignment MFS1 and SLC17A3

DIOPT Version :9

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 122/466 - (26%)
• Similarity: 218/466 - (46%)
• Gaps: 55/466 - (11%)

  Fly    19 FLLFLSIVVNYMAKFNAGVAVVAMTNAENTNP----------------------------NFPEY 55
            |..|.:|..|.:    ..:.:|||.|  :|:|                            ..|.|
Human    47 FCNFTTIAQNVI----MNITMVAMVN--STSPQSQLNDSSEVLPVDSFGGLSKAPKSLPAKAPVY 105

  Fly    56 DWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYC 120
            ||:...:..|..:..:|.|||....|:|..|.|.:..:.:|...::.|.:.||....: |.....
Human   106 DWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIPLATDF-GIVLLI 169

  Fly   121 AIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGI 185
            ..|:..||.|..:.....|....|.|.:||:||.::|.:|:..|...|:...|.: :.::|||.:
Human   170 VTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAILIGGFI-SETLGWPFV 233

  Fly   186 FYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETS----INSSRKAEEAELKATGPIPVP 246
            ||:..|||.:.|::|::...:.|....:|..:|..||.:|    :.||::            |:|
Human   234 FYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISSLKQQVGSSKQ------------PLP 286

  Fly   247 WKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYL 311
            .||:..|:|.|::.:......|..||:...:|.|::.|..::::.|.|.||||::.:||:..|..
Human   287 IKAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIVAWVIGMVGG 351

  Fly   312 IIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGS 376
            .:||.|||:....|| :||....:.....:|.::.:.:| |:....|..|:..:.|::.....|.
Human   352 YLADFLLTKKFRLIT-VRKIATILGSLPSSALIVSLPYL-NSGYITATALLTLSCGLSTLCQSGI 414

  Fly   377 TINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVY 441
            .||.:|::|.::..|||.....|:|.|::.|.:.|.::..|.: ..|:.||.:...:..:|.:.|
Human   415 YINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLSQDPE-FGWRNVFFLLFAVNLLGLLFY 478

  Fly   442 VAFGKMVNQPW 452
            :.||:...|.|
Human   479 LIFGEADVQEW 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	118/456 (26%)
		2A0114euk	19..456	CDD:129972	122/466 (26%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	122/466 (26%)
		MFS	98..481	CDD:119392	108/399 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750