Protein Alignment MFS1 and SLC17A2

DIOPT Version :9

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001273052.1
• Gene: SLC17A2 / 10246
• HGNCID: 10930
• Length: 478
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 112/475 - (23%)
• Similarity: 217/475 - (45%)
• Gaps: 39/475 - (8%)

  Fly     5 TNTGP-MIGQRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNA-------------------ENTN 49
            |..|| ....|:....::..|.......:.:..:|::||.|.                   .|::
Human     7 TRKGPDFCSLRYGLALIMHFSNFTMITQRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSS 71

  Fly    50 PNFPEYD-------WNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLI 107
            .:..|:|       |:...:..|.||..:|.|||....|:|...:||:..:....:.|:||.:..
Human    72 ISIKEFDTKASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFT 136

  Fly   108 PWCVSWGGWQAYCAIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFAS 172
            |....: |......:|...|:.||..:.......|.|.|..||::|..:|.:|...|:.:.:...
Human   137 PLAADF-GVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVG 200

  Fly   173 GLLAASSIGWPGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAEL 237
            ||: :.::.||.|||:....|.:.|::|:....:.|.....|...|..:|.:|:        |:.
Human   201 GLI-SQALSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSL--------AQQ 256

  Fly   238 KATGPIPVPWKAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLT 302
            .::....||.||:.|.:|.||:.:......|..:.:.|.:|.|::.:|.::::.:.:.|:||::.
Human   257 PSSPGRAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIA 321

  Fly   303 SWVMAFVYLIIADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVG 367
            :.....:...:||.||:|.::.:..:||..:|:...:|:...:.:.|:.::. .:.::|:....|
Human   322 AASCTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFVASSY-VITIILLILIPG 385

  Fly   368 INAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAV 432
            .:.....|..|||:|::|.:|..||||......|..|::....|.::..|.: ..|:.||.:||.
Human   386 TSNLCDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLISQDFE-SGWRNVFFLSAA 449

  Fly   433 IFCVGNIVYVAFGKMVNQPW 452
            :...|.:.|:.||:...|.|
Human   450 VNMFGLVFYLTFGQAELQDW 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	104/451 (23%)
		2A0114euk	19..456	CDD:129972	108/460 (23%)
SLC17A2	NP_001273052.1	2A0114euk	1..477	CDD:129972	112/475 (24%)
		MFS	81..461	CDD:119392	96/391 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750