Protein Alignment MFS1 and slc17a6

DIOPT Version :10

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_004913390.1
• Gene: slc17a6 / 101730310
• XenbaseID: XB-GENE-1011394
• Length: 583
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 150/518 - (28%)
• Similarity: 246/518 - (47%)
• Gaps: 54/518 - (10%)

  Fly    13 QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMTNAENTN------PNFPEYDWNEMERSYILSSFFW 71
            :|::...:..|...:::..:.|.|||:|.|.|....:      ....:::|:......|..||||
 Frog    69 RRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHHGGKIIKEKAKFNWDPEIVGMIHGSFFW 133

  Fly    72 GYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWC--VSWGGWQAYCAI--RMSMGLFQGF 132
            |||:||..||::..|..|......:.:.::.|.:|||..  |.:|     |.|  |:..||.:|.
 Frog   134 GYIVTQIPGGYIASRLAANRVFGAAIVLTSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGV 193

  Fly   133 LFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLWC 197
            .:|..|...:.|.|..||:||...:..|...|.::||..:|:|...: ||..:|||....|::|.
 Frog   194 TYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGCFGLVWY 257

  Fly   198 IVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPI---PVPWKAIWTSVPFWAL 259
            :.|.:.....|.:...|.:.|.||||.||..|       ....||:   ..||:..:||:|.:|:
 Frog   258 LFWILVSYESPAKHPTITDEERNYIEESIGES-------ANILGPVEKFKTPWRKFFTSMPVYAI 315

  Fly   260 MVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMS 324
            :|...|:||.:..|....|||...|...::....:.||:|:|...::..:...|||.|.::.|:|
 Frog   316 IVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILS 380

  Fly   325 ITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAG 389
            .|.:||.:|...|.:.|..|:.|.:  :..|.:|:..:...||.:..:..|..:|.:|::|.:|.
 Frog   381 TTTVRKIMNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYAS 443

  Fly   390 ILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDA 454
            |||||.|....:..::.||:||.:.| ...||:||.||:|:|::...|.|.|..|.....|||..
 Frog   444 ILMGISNGVGTLSGMVCPLIVGAMTK-HKSREEWQYVFLIAALVHYGGVIFYGIFASGEKQPWAD 507

  Fly   455 PD--------FMDKQR--------SSNLQEVGHSKALEA---------QGSEKVEEAKRNESE 492
            |:        |:::..        |.|....|.:|:..|         .|.||.||..:.:.:
 Frog   508 PEQTSDEKCGFINEDELAEEAGDISQNYINYGTAKSYGATTQMNTGWPNGWEKREEGVQGDGQ 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS_SLC17	18..445	CDD:340876	133/439 (30%)
slc17a6	XP_004913390.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	133/439 (30%)