Protein Alignment MFS1 and SLC17A4

DIOPT Version :9

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 117/465 - (25%)
• Similarity: 217/465 - (46%)
• Gaps: 38/465 - (8%)

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAMTN--AENTNPN------------------------F 52
            ||....:|.|.....|..:.|..:|:.||.|  |..:.||                        .
Human    36 RHGLALILQLCNFSIYTQQMNLSIAIPAMVNNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMA 100

  Fly    53 PEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQ 117
            |.|||:...:..||||..:|..|.....|::...:||:..:......|:.|.:.||...: .|..
Human   101 PAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAAN-AGVA 164

  Fly   118 AYCAIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGW 182
            ....:|:..|:.|..:....::....|.|..||::|..:|.:|...|:.:.:.|.||| ..:|||
Human   165 LLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLL-CQTIGW 228

  Fly   183 PGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPW 247
            |.:||:..|:|...|.:|:....:.|....||...|..||..|:        |:...:....:|.
Human   229 PYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSL--------AQQDCSPGWSLPI 285

  Fly   248 KAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLI 312
            :|:..|:|.||::|:..|:.|.:.|:....|.|::.||..:::.:.:.||||::...:...:..:
Human   286 RAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGL 350

  Fly   313 IADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGST 377
            :||.||:|.|:.:..|||...:|....|:..|:.:.:: .:..::.:..:..:..|::....|:.
Human   351 LADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWV-RSSHSMTMTFLVLSSAISSFCESGAL 414

  Fly   378 INTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYV 442
            :|.:|::|.:.|.|.|::...::|...::|...|..:..|.: ..|:.||::||.:...|.:.|:
Human   415 VNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSE-FGWRNVFLLSAAVNISGLVFYL 478

  Fly   443 AFGKMVNQPW 452
            .||:...|.|
Human   479 IFGRADVQDW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	111/451 (25%)
		2A0114euk	19..456	CDD:129972	115/460 (25%)
SLC17A4	NP_005486.1	UhpC	30..491	CDD:332119	117/465 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740