Protein Alignment MFS1 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 117/465 - (25%)
• Similarity: 217/465 - (46%)
• Gaps: 38/465 - (8%)

  Fly    14 RHLQTFLLFLSIVVNYMAKFNAGVAVVAMTN--AENTNPN------------------------F 52
            ||....:|.|.....|..:.|..:|:.||.|  |..:.||                        .
Human    36 RHGLALILQLCNFSIYTQQMNLSIAIPAMVNNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMA 100

  Fly    53 PEYDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQ 117
            |.|||:...:..||||..:|..|.....|::...:||:..:......|:.|.:.||...: .|..
Human   101 PAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAAN-AGVA 164

  Fly   118 AYCAIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGW 182
            ....:|:..|:.|..:....::....|.|..||::|..:|.:|...|:.:.:.|.||| ..:|||
Human   165 LLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLL-CQTIGW 228

  Fly   183 PGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPW 247
            |.:||:..|:|...|.:|:....:.|....||...|..||..|:        |:...:....:|.
Human   229 PYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSL--------AQQDCSPGWSLPI 285

  Fly   248 KAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLI 312
            :|:..|:|.||::|:..|:.|.:.|:....|.|::.||..:::.:.:.||||::...:...:..:
Human   286 RAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGL 350

  Fly   313 IADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGST 377
            :||.||:|.|:.:..|||...:|....|:..|:.:.:: .:..::.:..:..:..|::....|:.
Human   351 LADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWV-RSSHSMTMTFLVLSSAISSFCESGAL 414

  Fly   378 INTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYV 442
            :|.:|::|.:.|.|.|::...::|...::|...|..:..|.: ..|:.||::||.:...|.:.|:
Human   415 VNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSE-FGWRNVFLLSAAVNISGLVFYL 478

  Fly   443 AFGKMVNQPW 452
            .||:...|.|
Human   479 IFGRADVQDW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS_SLC17	18..445	CDD:340876	111/452 (25%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	111/452 (25%)