DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30203 and spon2

DIOPT Version :9

Sequence 1:	NP_725128.2	Gene:	CG30203 / 246514	FlyBaseID:	FBgn0050203	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	XP_031757621.1	Gene:	spon2 / 780015	XenbaseID:	XB-GENE-945214	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	321	Identity:	98/321 - (30%)
Similarity:	137/321 - (42%)	Gaps:	41/321 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 ELNSLTPPLE-TCCACDE-AKYEIVLERKWARNTHWKDF----PSEDWRTRLGEVIGASHSHSYR 224
            |.:|..|..| :.|..:| |||.||...||.:.:..|.:    |...|.|    ::|.:||..|.
Frog    38 EYSSCLPLSEDSICTAEEIAKYSIVFTGKWTQASFPKQYPLYRPPAQWST----LLGVTHSSDYH 98

  Fly   225 YWAYGGRASKGMKELAEHGATRTLENEIR---ENTQNGEVRTIIKAPGIPYRPKTFGTTLANARL 286
            .|.....||.|:::.||.|....|..||.   |..|:  |..|.....|     :.||..|:...
Frog    99 MWKKLEPASNGVRDFAEKGEAWPLMKEIETAGEKIQS--VHGIFSTASI-----SGGTGQASTEF 156

  Fly   287 D--PVHHQISLAAKIDPSPDWILGVAGLELCLSNCTWLERKVLNLYPWDIGTDSGPSYMSSDEPQ 349
            :  ..|..:|...:|.|||||.:||..|.|| ....|.:...|.|:|:|.|||||.::.|.:...
Frog   157 EAHSRHPFVSFMVRIVPSPDWFVGVDTLNLC-EGKHWKQTATLELHPYDAGTDSGFTFSSPNFAT 220

  Fly   350 VPPDVVRRITSSYPSDHRSPFYDDTGAPMKPLATLYLTRKKLYI--------------RECEEVP 400
            :|..:|..||:|.||...:.||......:.|:|.:..|:.|..:              .|..|..
Frog   221 IPQGIVTEITASSPSHPANSFYYPRLKSLPPIAKVVFTKVKGRLSSFLDIVSNVTTTGNEIAEHI 285

  Fly   401 QEGPLECAVHPWNEWTNCSTRCG-QGYSHRQRSFK-NPNLAANFNCDRRLEEFRQCQGTQC 459
            .|.||:|.|..|:.|..|...|| .|...|.|..: .|  |.|......|.|.::|....|
Frog   286 LETPLDCEVSVWSSWGLCRGSCGTAGVKSRTRYIRLKP--ANNGTACPALNEDKECDPENC 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30203	NP_725128.2	Reeler	18..160	CDD:260081
		Spond_N	183..372	CDD:283999	65/197 (33%)
		TSP1	411..459	CDD:214559	14/49 (29%)
		TSP1	492..541	CDD:214559
		KU	<739..773	CDD:197529
spon2	XP_031757621.1	Spond_N	57..244	CDD:399462	66/198 (33%)
spon2	XP_031757621.1	TSP1_spondin	292..344	CDD:408798	16/53 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240419at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920