DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18853 and TRMO

DIOPT Version :9

Sequence 1:	NP_724615.1	Gene:	CG18853 / 246511	FlyBaseID:	FBgn0042173	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001358586.1	Gene:	TRMO / 51531	HGNCID:	30967	Length:	441	Species:	Homo sapiens

Alignment Length:	124	Identity:	41/124 - (33%)
Similarity:	60/124 - (48%)	Gaps:	15/124 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GHCLGEDYAHFRPIGVIRTAFPEKRAVPRQSIVGSRLRGIIQLNDGVFTNPEHSLEGLEDFSHLW 154
            |:.|.|      |:|.:.:.|..|...|||..:.|..|..:::...:|.||||||.|||.|||:|
Human    26 GNLLTE------PVGYLESCFSAKNGTPRQPSICSYSRACLRIRKRIFNNPEHSLMGLEQFSHVW 84

  Fly   155 LIYHFHRNNSHPKAKADNFCFYNEHYDSLKGLSSWAYQTLDAHRKDKRDPCYSLEELEK 213
            :::.||: |.|...||      ......|.|..:..:.|...||.:...  .:|.:|||
Human    85 ILFVFHK-NGHLSCKA------KVQPPRLNGAKTGVFSTRSPHRPNAIG--LTLAKLEK 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18853	NP_724615.1	UPF0066	100..>163	CDD:294485	25/62 (40%)
TRMO	NP_001358586.1	UPF0066	45..164	CDD:376698	34/99 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..231
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..284
		TrmO_C	335..403	CDD:375815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7614
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483097at2759
OrthoFinder	1	1.000	-	-		FOG0005744
OrthoInspector	1	1.000	-	-		otm41071
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4138
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.770