DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18853 and Cry2

DIOPT Version :9

Sequence 1:NP_724615.1 Gene:CG18853 / 246511 FlyBaseID:FBgn0042173 Length:330 Species:Drosophila melanogaster
Sequence 2:NP_034093.1 Gene:Cry2 / 12953 MGIID:1270859 Length:592 Species:Mus musculus


Alignment Length:338 Identity:70/338 - (20%)
Similarity:104/338 - (30%) Gaps:109/338 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 ITRLLQDFRCEGCANNNKSAKDKVAGEKQEHQHQQQTQDQQTGQGQSNYTNGGHCLGE------- 95
            :|||..::..|.......:|..|:|.|                .|....|...|.|.:       
Mouse   111 VTRLTFEYDSEPFGKERDAAIMKMAKE----------------AGVEVVTENSHTLYDLDRIIEL 159

  Fly    96 -------DYAHFRPIGVIRTAFPEKRAVPRQSIVGSRLRGIIQLN-DGVFTNPEHSLE------- 145
                   .|..|:.: :.|...|:|.||...|......|..||.| |..:..|  |||       
Mouse   160 NGQKPPLTYKRFQAL-ISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVP--SLEELGFPTE 221

  Fly   146 --------GLEDFSHLWLIYHFHR-----NNSHPKAKADNFCFYNEHYDSLKGLSSWA------- 190
                    |.|..:...|..|..|     |...|:..|      |....|..|||.:.       
Mouse   222 GLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA------NSLLASPTGLSPYLRFGCLSC 280

  Fly   191 ----YQTLDAHRKDKRDPCYSLEELEKSLTYDDLWNSAQLQLVREGKMHGFLRMYWAKKI---LE 248
                |:..|.::|.||:....| .|...|.:.:.:.:|.....|..:|.|       ..|   :.
Mouse   281 RLFYYRLWDLYKKVKRNSTPPL-SLFGQLLWREFFYTAATNNPRFDRMEG-------NPICIQIP 337

  Fly   249 WTATPEHALEYAILLNDKYSLDGRDPNGYVGCMW---------SIGGVHDMGWKERAIF---GKV 301
            |...||...::|              .|..|..|         ..|.:|.:.....|.|   |.:
Mouse   338 WDRNPEALAKWA--------------EGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDL 388

  Fly   302 RYMNYQGCRRKFD 314
             :::::...|.||
Mouse   389 -WVSWESGVRVFD 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18853NP_724615.1 UPF0066 100..>163 CDD:294485 21/83 (25%)
Cry2NP_034093.1 PhrB 21..509 CDD:223492 70/338 (21%)
FAD_binding_7 306..504 CDD:377037 21/117 (18%)
Required for inhibition of CLOCK-ARNTL-mediated transcription. /evidence=ECO:0000250|UniProtKB:P97784 389..488 3/12 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..592
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0415
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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