DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG30187 and Klk1b16

DIOPT Version :10

Sequence 1:NP_001246475.2 Gene:CG30187 / 246509 FlyBaseID:FBgn0050187 Length:500 Species:Drosophila melanogaster
Sequence 2:NP_032480.1 Gene:Klk1b16 / 16615 MGIID:891982 Length:261 Species:Mus musculus


Alignment Length:278 Identity:82/278 - (29%)
Similarity:120/278 - (43%) Gaps:48/278 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 WFLKDVGASIFLD-QICGINIA----LKITGGHNAAFQNSVWMAAVHNRTHFICGGTLIHKRFVL 72
            |||     .:||. .:.||:.|    .:|.||......:..|..||:.....||||.|:.:.:||
Mouse     2 WFL-----ILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVL 61

  Fly    73 TAAHCIVDQDVQSVSLG---AYNKSDPADRKDVITAVVHSSFDVR----------ASYENDIGLL 124
            |||||.||:  ..|.||   .:.:...|..:.|..:..|..|::.          |.:.||:.||
Mouse    62 TAAHCYVDE--CEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLL 124

  Fly   125 KLSSDVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNK--TSDILQTIILNHLDREEC 187
            :||.......:::||.:...:...:     .|....|||::...|  ..|.||.:....|..|.|
Mouse   125 RLSKPADITDVVKPIDLPTKEPKLD-----STCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENC 184

  Fly   188 YMELSVYPSEKQICA---GVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGV 249
            .....:..::..:|.   |...| .|.|||||||..|..:|         |.:|:|...|...||
Mouse   185 AKAYLLKVTDVMLCTIEMGEDKG-PCVGDSGGPLICDGVLQ---------GTVSIGPDPCGIPGV 239

  Fly   250 ---YTDLMSFADWIKMTI 264
               ||:|:.|..|||.|:
Mouse   240 SAIYTNLVKFNSWIKDTM 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30187NP_001246475.2 Tryp_SPc 35..260 CDD:214473 70/245 (29%)
Trypsin 316..>384 CDD:459667
Klk1b16NP_032480.1 Tryp_SPc 25..256 CDD:238113 73/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.