DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AIMP3 and VARS1

DIOPT Version :9

Sequence 1:	NP_660194.1	Gene:	AIMP3 / 246507	FlyBaseID:	FBgn0050185	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	XP_005249419.1	Gene:	VARS1 / 7407	HGNCID:	12651	Length:	1265	Species:	Homo sapiens

Alignment Length:	108	Identity:	27/108 - (25%)
Similarity:	43/108 - (39%)	Gaps:	27/108 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 SRASREVEAQVYQWIEFSVLYVAP----------GSKDKYVSKQ--------LLADFNKLFASKS 107
            |||:    ..|.||:.::...:.|          |.:......|        .|:...:.....:
Human    90 SRAA----VLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEWLRLHT 150

  Fly   108 YLVGHFITLADLAVYYAI---YDLVKSLSPVDKEVYLNLSRWF 147
            ||.|...||||||...|:   :..|  |.|..:.::.|::|||
Human   151 YLAGEAPTLADLAAVTALLLPFRYV--LDPPARRIWNNVTRWF 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AIMP3	NP_660194.1	GST_C_AIMP3	65..166	CDD:198338	24/104 (23%)
VARS1	XP_005249419.1	GstA	<56..203	CDD:223698	27/108 (25%)
		GST_C_ValRS_N	92..213	CDD:198327	25/106 (24%)
		PTZ00419	283..1265	CDD:240411
		ValRS_core	336..939	CDD:185677
		tRNA-synt_1_2	514..>610	CDD:290334
		Anticodon_Ia_Val	939..1076	CDD:153416
		Val_tRNA-synt_C	1197..1259	CDD:287436
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810